Literature DB >> 19346371

The Santa Lucia strain of Plasmodium falciparum in Aotus monkeys.

William E Collins1, Joann S Sullivan, Allison Williams, G Gale Galland, Douglas Nace, Tyrone Williams, John W Barnwell.   

Abstract

The Santa Lucia strain of Plasmodium falciparum was studied in 150 Aotus lemurinus griseimembra, 30 A. azarae boliviensis, 103 A. nancymaae, and 121 A. vociferans monkeys. All four of these splenectomized hosts supported the production of gametocytes infective to Anopheles freeborni mosquitoes. Transmission through sporozoites from An. freeborni, An. stephensi, An. maculatus, and An. albimanus mosquitoes was successful to all four species of Aotus on a total of 100 occasions with a median pre-patent period of 21 days. For the production of infective mosquitoes for vaccine challenge studies, A. l. griseimembra and A. vociferans were the most predictable hosts.

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Year:  2009        PMID: 19346371

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN: 0002-9637            Impact factor:   2.345


  3 in total

1.  Transgenic parasites stably expressing full-length Plasmodium falciparum circumsporozoite protein as a model for vaccine down-selection in mice using sterile protection as an endpoint.

Authors:  Michael D Porter; Jennifer Nicki; Christopher D Pool; Margot DeBot; Ratish M Illam; Clara Brando; Brooke Bozick; Patricia De La Vega; Divya Angra; Roberta Spaccapelo; Andrea Crisanti; Jittawadee R Murphy; Jason W Bennett; Robert J Schwenk; Christian F Ockenhouse; Sheetij Dutta
Journal:  Clin Vaccine Immunol       Date:  2013-03-27

2.  A humanized mouse model for sequestration of Plasmodium falciparum sexual stages and in vivo evaluation of gametocytidal drugs.

Authors:  Yoann Duffier; Audrey Lorthiois; Pau Cisteró; Florian Dupuy; Grégory Jouvion; Laurence Fiette; Dominique Mazier; Alfredo Mayor; Catherine Lavazec; Alicia Moreno Sabater
Journal:  Sci Rep       Date:  2016-10-12       Impact factor: 4.379

3.  A chemokine-fusion vaccine targeting immature dendritic cells elicits elevated antibody responses to malaria sporozoites in infant macaques.

Authors:  Kun Luo; James T Gordy; Fidel Zavala; Richard B Markham
Journal:  Sci Rep       Date:  2021-01-13       Impact factor: 4.379

  3 in total

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