Literature DB >> 19346

Cimetidine and the gastric mucosal barrier.

G S Kenyon, I F Ansell, D C Carter.   

Abstract

The histamine H2-receptor antagonist, cimetidine, when given topically or parenterally, did not affect net luminal Na+ gain or net luminal H+ loss in vagally-denervated pouches of antrectomised dogs. Cimetidine did not affect disruption of the mucosal barrier by 5 mmol/l or 20 mmol/l sodium taurocholate.

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Year:  1977        PMID: 19346      PMCID: PMC1411712          DOI: 10.1136/gut.18.8.631

Source DB:  PubMed          Journal:  Gut        ISSN: 0017-5749            Impact factor:   23.059


  16 in total

1.  GASTRIC MUCOSAL INJURY BY FATTY AND ACETYLSALICYLIC ACIDS.

Authors:  H W DAVENPORT
Journal:  Gastroenterology       Date:  1964-03       Impact factor: 22.682

2.  Proceedings: Role of histamine receptors in the pathophysiology of gastric mucosal damage.

Authors:  W D Rees; J Rhodes; M H Wheeler; M E Meek; R G Newcombe
Journal:  Gut       Date:  1976-05       Impact factor: 23.059

3.  Proceedings: A controlled trial of H2-receptor antagonists in prophylaxis of bleeding from gastrointestinal erosions in fulminant hepatic failure.

Authors:  R J Bailey; B R Macdougall; R Williams
Journal:  Gut       Date:  1976-05       Impact factor: 23.059

4.  Histamine liberation by gastric mucosa of pylorus-ligated rats damaged by acetic or salicylic acids.

Authors:  L R Johnson
Journal:  Proc Soc Exp Biol Med       Date:  1966-02

5.  Fluid produced by the gastric mucosa during damage by acetic and salicylic acids.

Authors:  H W Davenport
Journal:  Gastroenterology       Date:  1966-04       Impact factor: 22.682

6.  Source of the histamine released during damage to the gastric mucosa by acetic acid.

Authors:  L R Johnson
Journal:  Gastroenterology       Date:  1968-01       Impact factor: 22.682

7.  Definition and antagonism of histamine H 2 -receptors.

Authors:  J W Black; W A Duncan; C J Durant; C R Ganellin; E M Parsons
Journal:  Nature       Date:  1972-04-21       Impact factor: 49.962

8.  Inhibition of nocturnal acid secretion in duodenal ulcer by one oral dose of metiamide.

Authors:  G J Milton-Thompson; J G Williams; D J Jenkins; J J Misiewicz
Journal:  Lancet       Date:  1974-04-20       Impact factor: 79.321

9.  Failure of ischemia to break the dog's gastric mucosal barrier.

Authors:  H W Davenport; L L Barr
Journal:  Gastroenterology       Date:  1973-10       Impact factor: 22.682

10.  Effect of gastric secretory inhibitors on the gastric mucosal barrier.

Authors:  P E O'Brien; D C Carter
Journal:  Gut       Date:  1975-06       Impact factor: 23.059

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  3 in total

1.  Increase in pepsin content in gastric mucosa during the course of aspirin- and taurocholate-induced gastric ulceration in rats.

Authors:  K Ohe; H Yokoya; T Kitaura; T Kunita; A Miyoshi
Journal:  Dig Dis Sci       Date:  1980-11       Impact factor: 3.199

2.  Effect of cimetidine and omeprazole on aspirin- and taurocholate-induced gastric mucosal damage in the rat.

Authors:  R J Utley; A S Salim; D C Carter
Journal:  Gut       Date:  1985-08       Impact factor: 23.059

3.  Bile salt-induced gastric mucosal damage and histamine receptor antagonists.

Authors:  H J Lewi; D C Carter
Journal:  Gut       Date:  1983-01       Impact factor: 23.059

  3 in total

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