| Literature DB >> 1934588 |
S V Kaveri1, G Dietrich, V Hurez, M D Kazatchkine.
Abstract
Intravenous immunoglobulin (IVIg) therapy is increasingly used in autoimmune diseases. Although its efficacy has only been established in a few specific antibody-mediated autoimmune conditions, accumulating evidence on the regulatory role of circulating immunoglobulins in the selection of peripheral B cell repertoires makes it an attractive potential therapeutic option to clinical immunologists. This overview briefly discusses the current use of IVIg in human autoimmune diseases with a particular emphasis on the possible mechanisms by which IVIg could suppress pathological autoimmune responses.Entities:
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Year: 1991 PMID: 1934588 PMCID: PMC1554132 DOI: 10.1111/j.1365-2249.1991.tb05794.x
Source DB: PubMed Journal: Clin Exp Immunol ISSN: 0009-9104 Impact factor: 4.330