Literature DB >> 19345438

Sulfonylurea treatment in a girl with neonatal diabetes (KCNJ11 R201H) and celiac disease: impact of low compliance to the gluten free diet.

Maurizio Delvecchio1, Clara Zecchino, Maria Felicia Faienza, Angelo Acquafredda, Fabrizio Barbetti, Luciano Cavallo.   

Abstract

A girl with celiac disease and KCNJ11 mutation was transferred to glibenclamide when 19.8 years old. When her compliance to the gluten free diet worsened, her metabolic control deteriorated. Since glibenclamide is absorbed in the intestine, its absorption seems to be impaired by chronic malabsorption, increasing the risk of hyperglycaemia.

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Year:  2009        PMID: 19345438     DOI: 10.1016/j.diabres.2009.02.024

Source DB:  PubMed          Journal:  Diabetes Res Clin Pract        ISSN: 0168-8227            Impact factor:   5.602


  1 in total

1.  Case report: coeliac disease as a cause of secondary failure of glibenclamide therapy in a patient with permanent neonatal diabetes due to KCNJ11/R201C mutation.

Authors:  Dario Iafusco; Angela Zanfardino; Alessia Piscopo; Francesca Casaburo; Angelica De Nigris; Salvatore Alfiero; Giuseppina Russo; Mattia Arenella; Maria Cecilia Russo; Fabrizio Barbetti
Journal:  Diabetologia       Date:  2021-05-14       Impact factor: 10.122

  1 in total

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