| Literature DB >> 19345383 |
Jean Rodolphe Chouna1, Pepin Alango Nkeng-Efouet, Bruno Ndjakou Lenta, Krishna Prasad Devkota, Beate Neumann, Hans-Georg Stammler, Samuel Fon Kimbu, Norbert Sewald.
Abstract
Three endiandric acid derivatives, beilschmiedic acids A, B and C were isolated from the stem bark of Beilschmiedia anacardioides together with the known beta-sitosterol. Their structures were established by means of modern spectroscopic techniques. The relative configuration of compound 1 was determined by single crystal X-ray analysis. The antibacterial activities of compounds A,B,C were evaluated in vitro against five strains of microbes. Compound C showed strong activity against Bacillus subtilis, Micrococcus luteus and Streptococcus faecalis (MICs below 23 microM). This Compound was more active than the reference antibiotic ampicillin against B. subtilis and M. luteus.Entities:
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Year: 2009 PMID： 19345383 DOI： 10.1016/j.phytochem.2009.02.012
Source DB: PubMed Journal: Phytochemistry ISSN： 0031-9422 Impact factor: 4.072