Literature DB >> 19345342

The structure of Cryptococcus neoformans galactoxylomannan contains beta-D-glucuronic acid.

Christian Heiss1, J Stacey Klutts, Zhirui Wang, Tamara L Doering, Parastoo Azadi.   

Abstract

The structure of galactoxylomannan, a capsular polysaccharide from the opportunistic yeast Cryptococcus neoformans, was re-examined by NMR spectroscopy and GC-MS. The residue that is 3-linked to the side chain galactose and was previously assigned as beta-D-xylose [Vaishnav, V. V.; Bacon, B. E.; O'Neill, M.; Cherniak, R. Carbohydr. Res.1998, 306, 315-330] was determined to be beta-D-glucuronic acid. A revised structure for this polymer is presented, along with a proposal that this compound be termed glucuronoxylomannogalactan (GXMGal).

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Year:  2009        PMID: 19345342      PMCID: PMC2695399          DOI: 10.1016/j.carres.2009.03.003

Source DB:  PubMed          Journal:  Carbohydr Res        ISSN: 0008-6215            Impact factor:   2.104


  8 in total

1.  A comprehensive procedure for preparation of partially methylated alditol acetates from glycoprotein carbohydrates.

Authors:  K R Anumula; P B Taylor
Journal:  Anal Biochem       Date:  1992-05-15       Impact factor: 3.365

Review 2.  Cryptococcosis.

Authors:  Methee Chayakulkeeree; John R Perfect
Journal:  Infect Dis Clin North Am       Date:  2006-09       Impact factor: 5.982

3.  Cell-wall polysaccharides from the marine green alga Ulva "rigida" (Ulvales, Chlorophyta)--NMR analysis of ulvan oligosaccharides.

Authors:  M Lahaye; B Ray
Journal:  Carbohydr Res       Date:  1996-03-22       Impact factor: 2.104

4.  Encapsulation and melanin formation as indicators of virulence in Cryptococcus neoformans.

Authors:  K J Kwon-Chung; J C Rhodes
Journal:  Infect Immun       Date:  1986-01       Impact factor: 3.441

5.  Carbon-13 magnetic resonance studies of amino acids and peptides.

Authors:  W J Horsley; H Sternlicht
Journal:  J Am Chem Soc       Date:  1968-07-03       Impact factor: 15.419

6.  Cryptococcus neoformans chemotyping by quantitative analysis of 1H nuclear magnetic resonance spectra of glucuronoxylomannans with a computer-simulated artificial neural network.

Authors:  R Cherniak; H Valafar; L C Morris; F Valafar
Journal:  Clin Diagn Lab Immunol       Date:  1998-03

7.  Cryptococcal xylosyltransferase 1 (Cxt1p) from Cryptococcus neoformans plays a direct role in the synthesis of capsule polysaccharides.

Authors:  J Stacey Klutts; Tamara L Doering
Journal:  J Biol Chem       Date:  2008-03-17       Impact factor: 5.157

8.  Structural characterization of the galactoxylomannan of Cryptococcus neoformans Cap67.

Authors:  V V Vaishnav; B E Bacon; M O'Neill; R Cherniak
Journal:  Carbohydr Res       Date:  1998-01       Impact factor: 2.104

  8 in total
  52 in total

Review 1.  Emerging themes in cryptococcal capsule synthesis.

Authors:  Pardeep Kumar; Meng Yang; Brian C Haynes; Michael L Skowyra; Tamara L Doering
Journal:  Curr Opin Struct Biol       Date:  2011-09-01       Impact factor: 6.809

2.  Interspecies Competition Impacts Targeted Manipulation of Human Gut Bacteria by Fiber-Derived Glycans.

Authors:  Michael L Patnode; Zachary W Beller; Nathan D Han; Jiye Cheng; Samantha L Peters; Nicolas Terrapon; Bernard Henrissat; Sophie Le Gall; Luc Saulnier; David K Hayashi; Alexandra Meynier; Sophie Vinoy; Richard J Giannone; Robert L Hettich; Jeffrey I Gordon
Journal:  Cell       Date:  2019-09-19       Impact factor: 41.582

3.  Evidence for branching in cryptococcal capsular polysaccharides and consequences on its biological activity.

Authors:  Radames J B Cordero; Susana Frases; Allan J Guimaräes; Johanna Rivera; Arturo Casadevall
Journal:  Mol Microbiol       Date:  2011-01-05       Impact factor: 3.501

4.  Regulation of Neurospora crassa cell wall remodeling via the cot-1 pathway is mediated by gul-1.

Authors:  Inbal Herold; Oded Yarden
Journal:  Curr Genet       Date:  2016-06-30       Impact factor: 3.886

5.  Sugar release and growth of biofuel crops are improved by downregulation of pectin biosynthesis.

Authors:  Ajaya K Biswal; Melani A Atmodjo; Mi Li; Holly L Baxter; Chang Geun Yoo; Yunqiao Pu; Yi-Ching Lee; Mitra Mazarei; Ian M Black; Ji-Yi Zhang; Hema Ramanna; Adam L Bray; Zachary R King; Peter R LaFayette; Sivakumar Pattathil; Bryon S Donohoe; Sushree S Mohanty; David Ryno; Kelsey Yee; Olivia A Thompson; Miguel Rodriguez; Alexandru Dumitrache; Jace Natzke; Kim Winkeler; Cassandra Collins; Xiaohan Yang; Li Tan; Robert W Sykes; Erica L Gjersing; Angela Ziebell; Geoffrey B Turner; Stephen R Decker; Michael G Hahn; Brian H Davison; Michael K Udvardi; Jonathan R Mielenz; Mark F Davis; Richard S Nelson; Wayne A Parrott; Arthur J Ragauskas; C Neal Stewart; Debra Mohnen
Journal:  Nat Biotechnol       Date:  2018-02-12       Impact factor: 54.908

6.  Evaluation of Cryptococcus neoformans galactoxylomannan-protein conjugate as vaccine candidate against murine cryptococcosis.

Authors:  Siu-Kei Chow; Arturo Casadevall
Journal:  Vaccine       Date:  2011-01-14       Impact factor: 3.641

7.  Ultrastructural and biochemical analyses reveal cell wall remodelling in lichen-forming microalgae submitted to cyclic desiccation-rehydration.

Authors:  María González-Hourcade; Marcia R Braga; Eva M Del Campo; Carmen Ascaso; Cristina Patiño; Leonardo M Casano
Journal:  Ann Bot       Date:  2020-03-09       Impact factor: 4.357

8.  Pbx proteins in Cryptococcus neoformans cell wall remodeling and capsule assembly.

Authors:  Pardeep Kumar; Christian Heiss; Felipe H Santiago-Tirado; Ian Black; Parastoo Azadi; Tamara L Doering
Journal:  Eukaryot Cell       Date:  2014-02-28

9.  Cryptococcus neoformans UGT1 encodes a UDP-Galactose/UDP-GalNAc transporter.

Authors:  Lucy X Li; Angel Ashikov; Hong Liu; Cara L Griffith; Hans Bakker; Tamara L Doering
Journal:  Glycobiology       Date:  2016-08-03       Impact factor: 4.313

Review 10.  How sweet it is! Cell wall biogenesis and polysaccharide capsule formation in Cryptococcus neoformans.

Authors:  Tamara Lea Doering
Journal:  Annu Rev Microbiol       Date:  2009       Impact factor: 15.500

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