| Literature DB >> 19345183 |
Steven J Bensinger1, Peter Tontonoz.
Abstract
Mutations in the gene encoding the orphan nuclear receptor Nurr1 are linked to a rare familial form of Parkinson's disease. By examining the function of its mouse homolog, Saijo et al. (2009) provide evidence that Nurr1 protects dopaminergic neurons by suppressing inflammatory gene expression in astrocytes and microglia.Entities:
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Year: 2009 PMID： 19345183 DOI： 10.1016/j.cell.2009.03.024
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582