Literature DB >> 19344880

Long-term neurodevelopmental outcome after fetal arrhythmia.

Enrico Lopriore1, Muhammed I Aziz, Helene T Nagel, Nico A Blom, Lieke Rozendaal, Humphrey H H Kanhai, Frank P H A Vandenbussche.   

Abstract

OBJECTIVE: The purpose of this study was to determine the long-term neurodevelopmental outcome in fetuses with severe tachy- or bradyarrhythmia. STUDY
DESIGN: This was a follow-up study to assess the neurologic, mental, and psychomotor development in cases with fetal cardiac arrhythmia.
RESULTS: A total of 44 fetuses were diagnosed with fetal tachy- or bradyarrhythmia: 28 fetuses had supraventricular tachycardia (SVT); 7 fetuses had atrial flutter (AF), and 9 fetuses had atrioventricular block (AVB). The mortality rate was low (6%; 2/35 fetuses) in the SVT and AF groups and high in the AVB group (78%; 7/9 fetuses). Six patients were lost to follow-up evaluation (14%). Neurodevelopmental outcome was normal in all survivors in the SVT and AF groups, except for 1 patient who experienced plexus brachialis injury because of shoulder dystocia. Two of the 3 survivors in the AVB group had severe developmental delay.
CONCLUSION: The mortality rate and neurodevelopmental impairment in infants with SVT and AF are low, but the mortality rate in infants with AVB is elevated.

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Year:  2009        PMID: 19344880     DOI: 10.1016/j.ajog.2009.02.002

Source DB:  PubMed          Journal:  Am J Obstet Gynecol        ISSN: 0002-9378            Impact factor:   8.661


  2 in total

1.  Transplacental digoxin therapy for fetal atrial flutter with hydrops fetalis.

Authors:  Kai-Yu Zhou; Yi-Min Hua; Qi Zhu
Journal:  World J Pediatr       Date:  2011-08-27       Impact factor: 2.764

2.  Antenatal antiarrhythmic treatment for fetal tachyarrhythmias: a study protocol for a prospective multicentre trial.

Authors:  Takekazu Miyoshi; Yasuki Maeno; Haruhiko Sago; Noboru Inamura; Satoshi Yasukochi; Motoyoshi Kawataki; Hitoshi Horigome; Hitoshi Yoda; Mio Taketazu; Makio Shozu; Masaki Nii; Akiko Hagiwara; Hitoshi Kato; Wataru Shimizu; Isao Shiraishi; Heima Sakaguchi; Keiko Ueda; Shinji Katsuragi; Tomoaki Ikeda; Haruko Yamamoto; Toshimitsu Hamasaki
Journal:  BMJ Open       Date:  2017-08-29       Impact factor: 2.692

  2 in total

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