Literature DB >> 19344628

Efficient methods for studying stochastic disease and population dynamics.

M J Keeling1, J V Ross.   

Abstract

Stochastic ecological and epidemiological models are now routinely used to inform management and decision making throughout conservation and public-health. A difficulty with the use of such models is the need to resort to simulation methods when the population size (and hence the size of the state space) becomes large, resulting in the need for a large amount of computation to achieve statistical confidence in results. Here we present two methods that allow evaluation of all quantities associated with one- (and higher) dimensional Markov processes with large state spaces. We illustrate these methods using SIS disease dynamics and studying species that are affected by catastrophic events. The methods allow the possibility of extending exact Markov methods to real-world problems, providing techniques for efficient parameterisation and subsequent analysis.

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Year:  2009        PMID: 19344628     DOI: 10.1016/j.tpb.2009.01.003

Source DB:  PubMed          Journal:  Theor Popul Biol        ISSN: 0040-5809            Impact factor:   1.570


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