Literature DB >> 19343099

Cardiovascular Consequences of Obesity and Targets for Treatment.

Bettina Mittendorfer1, Linda R Peterson.   

Abstract

Obesity is a risk factor for cardiovascular disease, including coronary artery disease and heart failure, but the mechanisms by which it may cause them are not completely clear. Currently, therapies aimed at obesity-related cardiovascular disease include weight loss strategies and reduction of the other risk factors that are associated with obesity and cardiovascular disease. Other pathways with for potential drug development for obesity-related CVD are also discussed.

Entities:  

Year:  2008        PMID： 19343099      PMCID： PMC2630250          DOI： 10.1016/j.ddstr.2008.07.001

Source DB:  PubMed          Journal:  Drug Discov Today Ther Strateg        ISSN： 1740-6773


  77 in total

1.  Imaging aortic matrix metabolism: mirabile visu!

Authors:  Dwight A Towler
Journal:  Circulation       Date:  2007-01-23       Impact factor: 29.690

Review 2.  Adipose tissue, inflammation and endothelial dysfunction.

Authors:  Jerzy Chudek; Andrzej Wiecek
Journal:  Pharmacol Rep       Date:  2006       Impact factor: 3.024

3.  Inflammation and hypertension: the search for a link.

Authors:  Paolo Pauletto; Marcello Rattazzi
Journal:  Nephrol Dial Transplant       Date:  2006-02-07       Impact factor: 5.992

Review 4.  Obesity and thrombosis.

Authors:  K A L Darvall; R C Sam; S H Silverman; A W Bradbury; D J Adam
Journal:  Eur J Vasc Endovasc Surg       Date:  2006-12-20       Impact factor: 7.069

5.  Effects of weight reduction on blood lipids and lipoproteins: a meta-analysis.

Authors:  A M Dattilo; P M Kris-Etherton
Journal:  Am J Clin Nutr       Date:  1992-08       Impact factor: 7.045

6.  Alterations in left ventricular structure and function in young healthy obese women: assessment by echocardiography and tissue Doppler imaging.

Authors:  Linda R Peterson; Alan D Waggoner; Kenneth B Schechtman; Timothy Meyer; Robert J Gropler; Benico Barzilai; Víctor G Dávila-Román
Journal:  J Am Coll Cardiol       Date:  2004-04-21       Impact factor: 24.094

7.  The influence of obesity on left ventricular filling and systolic function.

Authors:  M F Stoddard; K Tseuda; M Thomas; S Dillon; J Kupersmith
Journal:  Am Heart J       Date:  1992-09       Impact factor: 4.749

8.  Prevalence of the metabolic syndrome and its relation to all-cause and cardiovascular mortality in nondiabetic European men and women.

Authors:  Gang Hu; Qing Qiao; Jaakko Tuomilehto; Beverley Balkau; Knut Borch-Johnsen; Kalevi Pyorala
Journal:  Arch Intern Med       Date:  2004-05-24

9.  Location and regulation of rat angiotensinogen messenger RNA.

Authors:  L A Cassis; J Saye; M J Peach
Journal:  Hypertension       Date:  1988-06       Impact factor: 10.190

10.  IL-6 is produced by splenocytes derived from CMV-infected mice in response to CMV antigens, and induces MCP-1 production by endothelial cells: a new mechanistic paradigm for infection-induced atherogenesis.

Authors:  David Rott; Jianhui Zhu; Yi Fu Zhou; Mary Susan Burnett; Alexandra Zalles-Ganley; Stephen E Epstein
Journal:  Atherosclerosis       Date:  2003-10       Impact factor: 5.162
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  3 in total

Review 1.  New central targets for the treatment of obesity.

Authors:  Bruce J Sargent; Nicholas A Moore
Journal:  Br J Clin Pharmacol       Date:  2009-12       Impact factor: 4.335

2.  The risk of heart failure and cardiometabolic complications in obesity may be masked by an apparent healthy status of normal blood glucose.

Authors:  Shuchita Tiwari; Manish Mishra; Ashok Jadhav; Courtney Gerger; Paul Lee; Lynn Weber; Joseph Fomusi Ndisang
Journal:  Oxid Med Cell Longev       Date:  2013-12-14       Impact factor: 6.543

3.  Higher BMI is linked to an increased risk of heart attacks in European adults: a Mendelian randomisation study.

Authors:  Benjamin Adams; Lauren Jacocks; Hui Guo
Journal:  BMC Cardiovasc Disord       Date:  2020-05-29       Impact factor: 2.298
  3 in total

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