Armin Kalenka1, Anke Schwarz. 1. Department of Anaesthesiology and Surgical Intensive Care Medicine, University Medical Center Mannheim, Theodor Kutzer Ufer 1-3, Mannheim 68167, Germany. armin.kalenka@urz.uni-hd.de
Abstract
PURPOSE OF REVIEW: Parkinson's disease is the second most prevalent neurodegenerative disease and presents a particular anaesthetic challenge. The clinical features are described in detail, and recent advances in medical management and neurosurgical treatment options are highlighted. RECENT FINDINGS: Deep brain stimulation (DBS) has experienced a renaissance for selected patients. Potential drug interactions with anaesthetics are described and recommendations are made about suitable anaesthetic techniques, especially for DBS. In addition to the classic DBS in an awake state, stimulation under modified general anaesthesia seems possible in selected patients who are not suitable for awake craniotomy. SUMMARY: DBS is an attractive option for severely disabled patients with Parkinson's disease who pose a particular anaesthetic challenge.
PURPOSE OF REVIEW: Parkinson's disease is the second most prevalent neurodegenerative disease and presents a particular anaesthetic challenge. The clinical features are described in detail, and recent advances in medical management and neurosurgical treatment options are highlighted. RECENT FINDINGS: Deep brain stimulation (DBS) has experienced a renaissance for selected patients. Potential drug interactions with anaesthetics are described and recommendations are made about suitable anaesthetic techniques, especially for DBS. In addition to the classic DBS in an awake state, stimulation under modified general anaesthesia seems possible in selected patients who are not suitable for awake craniotomy. SUMMARY: DBS is an attractive option for severely disabled patients with Parkinson's disease who pose a particular anaesthetic challenge.
Authors: Amit Benady; Sean Zadik; Dan Eimerl; Sami Heymann; Hagai Bergman; Zvi Israel; Aeyal Raz Journal: Sci Rep Date: 2020-09-03 Impact factor: 4.379