D Pitot1, E Bouazza, R Chamlou, J Van de Stadt. 1. Clinic of Colorectal Surgery, Department of Digestive Surgery, Hôpital Erasme - ULB, Brussels, Belgium. Denis.pitot@skynet.be
Abstract
BACKGROUND: Although full bowel preparation, including mechanical washout and non-absorbable antibiotherapy, has been considered for decades as a prerequisite to any elective colorectal surgery, recent literature has suggested that this habit was perhaps unjustified. The aim of this study was to assess the safety of ileocolic, colocolic and colorectal anastomosis in the absence of pre-operative mechanical bowel preparation. METHODS: During a 1-year period, 59 consecutive patients underwent elective colorectal surgery with ileocolic, colocolic or colorectal anastomosis without any pre-operative preparation. This "non-prepared group" (NPG) was compared to a "control group" (CG) composed of the previous 127 consecutive cases of classically managed patients. To improve the statistical power we also compared the NPG to a "match-controlled group" (MCG) of 59 patients within the CG. Primary end-points were anastomotic leakage and abdominal infections. Secondary end-points were oral diet resume time and hospital stay. RESULTS: There were no differences between the 3 groups for age, gender, BMI, immunodepression status, anastomosis site and suture technique. There were no differences between NPG and CG or MCG for anastomotic leakage (3.5%, 4.7% and 6.8% respectively, NPG/CG p = 0.68 and NPG/MCG p = 0.4) or for infectious abdominal complications. Mean diet resume time was 1.4 (1-5) days in the NPG versus 3.4 (1-19) days in the CG and 3.1 (1-6) days in the MCG (p < 0.00001). Median length of postoperative hospital stay was 5 (2-81) days in the NPG versus 8 (4-100) and 8 (4-100) in the CG and the MCG respectively. CONCLUSIONS: In accordance with the recent literature, the present experience does not show any benefit of mechanical bowel preparation in elective colorectal resection. This suggests that bowel preparation could be omitted before this type of surgery.
BACKGROUND: Although full bowel preparation, including mechanical washout and non-absorbable antibiotherapy, has been considered for decades as a prerequisite to any elective colorectal surgery, recent literature has suggested that this habit was perhaps unjustified. The aim of this study was to assess the safety of ileocolic, colocolic and colorectal anastomosis in the absence of pre-operative mechanical bowel preparation. METHODS: During a 1-year period, 59 consecutive patients underwent elective colorectal surgery with ileocolic, colocolic or colorectal anastomosis without any pre-operative preparation. This "non-prepared group" (NPG) was compared to a "control group" (CG) composed of the previous 127 consecutive cases of classically managed patients. To improve the statistical power we also compared the NPG to a "match-controlled group" (MCG) of 59 patients within the CG. Primary end-points were anastomotic leakage and abdominal infections. Secondary end-points were oral diet resume time and hospital stay. RESULTS: There were no differences between the 3 groups for age, gender, BMI, immunodepression status, anastomosis site and suture technique. There were no differences between NPG and CG or MCG for anastomotic leakage (3.5%, 4.7% and 6.8% respectively, NPG/CG p = 0.68 and NPG/MCG p = 0.4) or for infectious abdominal complications. Mean diet resume time was 1.4 (1-5) days in the NPG versus 3.4 (1-19) days in the CG and 3.1 (1-6) days in the MCG (p < 0.00001). Median length of postoperative hospital stay was 5 (2-81) days in the NPG versus 8 (4-100) and 8 (4-100) in the CG and the MCG respectively. CONCLUSIONS: In accordance with the recent literature, the present experience does not show any benefit of mechanical bowel preparation in elective colorectal resection. This suggests that bowel preparation could be omitted before this type of surgery.