BACKGROUND: The association between nodal ratio and survival has not been assessed in squamous cell carcinomas of the head and neck. METHODS: This is a population-based analysis, using the Surveillance, Epidemiology, and End-Results database, to determine whether nodal ratio impacts survival in patients with oral cavity squamous cell carcinoma. RESULTS: Between 1988 and 2005, 2955 new diagnoses of N(1) or N(2) squamous cell carcinoma of the oral cavity were identified. The mean nodal ratio was 16.9%. Nodal ratio was found to be strongly statistically associated with overall survival in both univariate and multivariate analyses. Patients could be stratified into low- (0% to 6%), moderate- (6% to 12.5%), and high-risk (>12.5%) groups based on nodal ratio. CONCLUSIONS: In patients with squamous cell carcinoma of the oral cavity, an increased nodal ratio is a strong predictor of decreased survival. Risk of death can be stratified based on nodal ratio.
BACKGROUND: The association between nodal ratio and survival has not been assessed in squamous cell carcinomas of the head and neck. METHODS: This is a population-based analysis, using the Surveillance, Epidemiology, and End-Results database, to determine whether nodal ratio impacts survival in patients with oral cavity squamous cell carcinoma. RESULTS: Between 1988 and 2005, 2955 new diagnoses of N(1) or N(2) squamous cell carcinoma of the oral cavity were identified. The mean nodal ratio was 16.9%. Nodal ratio was found to be strongly statistically associated with overall survival in both univariate and multivariate analyses. Patients could be stratified into low- (0% to 6%), moderate- (6% to 12.5%), and high-risk (>12.5%) groups based on nodal ratio. CONCLUSIONS: In patients with squamous cell carcinoma of the oral cavity, an increased nodal ratio is a strong predictor of decreased survival. Risk of death can be stratified based on nodal ratio.
Authors: M de Ridder; C C M Marres; L E Smeele; M W M van den Brekel; M Hauptmann; A J M Balm; M L F van Velthuysen Journal: Virchows Arch Date: 2016-09-18 Impact factor: 4.064
Authors: Peter M Vila; Chaz L Stucken; Luc G T Morris; Marshall R Posner; Eric M Genden; Paolo Boffetta; Andrew G Sikora Journal: Eur Arch Otorhinolaryngol Date: 2013-11-05 Impact factor: 2.503
Authors: James J Jaber; Chad A Zender; Vikas Mehta; Kara Davis; Robert L Ferris; Pierre Lavertu; Rod Rezaee; Paul J Feustel; Jonas T Johnson Journal: Head Neck Date: 2014-01-13 Impact factor: 3.147
Authors: Oreste Iocca; Alessio Farcomeni; Armando De Virgilio; Pasquale Di Maio; Paweł Golusinski; Luca Malvezzi; Raul Pellini; Wojciech Golusinski; Christopher H Rassekh; Giuseppe Spriano Journal: Contemp Clin Trials Commun Date: 2019-01-14