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Literature DB >> 19339685

Transcriptional control of brown adipocyte development and physiological function--of mice and men.

Patrick Seale¹, Shingo Kajimura, Bruce M Spiegelman.

Abstract

The last several years have seen an explosion of information relating to the transcriptional control of brown fat cell development. At the same time, new data have emerged that clearly demonstrate that adult humans do indeed have substantial amounts of functioning brown adipose tissue (BAT). Together, these advances are stimulating a reassessment of the role of brown adipose tissue in human physiology and pathophysiology. These data have also opened up exciting new opportunities for the development of entirely novel classes of therapeutics for metabolic diseases like obesity and type 2 diabetes.

Entities: Disease Species

Mesh：

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Year: 2009 PMID： 19339685 PMCID： PMC2763499 DOI： 10.1101/gad.1779209

Source DB: PubMed Journal: Genes Dev ISSN： 0890-9369 Impact factor: 11.361

107 in total

1. Aberrant expression of the MEL1S gene identified in association with hypomethylation in adult T-cell leukemia cells.

Authors: Mika Yoshida; Kisato Nosaka; Jun-ichirou Yasunaga; Ichiro Nishikata; Kazuhiro Morishita; Masao Matsuoka
Journal: Blood Date: 2003-12-04 Impact factor: 22.113

Review 2. Brown adipose tissue: function and physiological significance.

Authors: Barbara Cannon; Jan Nedergaard
Journal: Physiol Rev Date: 2004-01 Impact factor: 37.312

3. Nuclear receptor corepressor RIP140 regulates fat accumulation.

Authors: Göran Leonardsson; Jenny H Steel; Mark Christian; Victoria Pocock; Stuart Milligan; Jimmy Bell; Po-Wah So; Gema Medina-Gomez; Antonio Vidal-Puig; Roger White; Malcolm G Parker
Journal: Proc Natl Acad Sci U S A Date: 2004-05-20 Impact factor: 11.205

4. Brown adipose tissue and nuclear medicine imaging.

Authors: Wolfgang A Weber
Journal: J Nucl Med Date: 2004-07 Impact factor: 10.057

5. Wnt10b inhibits development of white and brown adipose tissues.

Authors: Kenneth A Longo; Wendy S Wright; Sona Kang; Isabelle Gerin; Shian-Huey Chiang; Peter C Lucas; Mark R Opp; Ormond A MacDougald
Journal: J Biol Chem Date: 2004-06-09 Impact factor: 5.157

6. Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice.

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Journal: Cell Date: 2004-10-01 Impact factor: 41.582

7. Intense (18)F-FDG uptake in brown fat can be reduced pharmacologically.

Authors: Mitsuaki Tatsumi; James M Engles; Takayoshi Ishimori; O'Bod Nicely; Christian Cohade; Richard L Wahl
Journal: J Nucl Med Date: 2004-07 Impact factor: 10.057

8. p38 mitogen-activated protein kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene.

Authors: Wenhong Cao; Kiefer W Daniel; Jacques Robidoux; Pere Puigserver; Alexander V Medvedev; Xu Bai; Lisa M Floering; Bruce M Spiegelman; Sheila Collins
Journal: Mol Cell Biol Date: 2004-04 Impact factor: 4.272

9. Retinoblastoma protein functions as a molecular switch determining white versus brown adipocyte differentiation.

Authors: Jacob B Hansen; Claus Jørgensen; Rasmus K Petersen; Philip Hallenborg; Rita De Matteis; Hans A Bøye; Natasa Petrovic; Sven Enerbäck; Jan Nedergaard; Saverio Cinti; Hein te Riele; Karsten Kristiansen
Journal: Proc Natl Acad Sci U S A Date: 2004-03-15 Impact factor: 11.205

10. Commitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineage.

Authors: Qi-Qun Tang; Tamara C Otto; M Daniel Lane
Journal: Proc Natl Acad Sci U S A Date: 2004-06-21 Impact factor: 11.205

124 in total

Review 1. Enzymatic intracrine regulation of white adipose tissue.

Authors: David DiSilvestro; Jennifer Petrosino; Ayat Aldoori; Emiliano Melgar-Bermudez; Alexandra Wells; Ouliana Ziouzenkova
Journal: Horm Mol Biol Clin Investig Date: 2014-07

Review 2. Brown adipose tissue--a new role in humans?

Authors: Martin E Lidell; Sven Enerbäck
Journal: Nat Rev Endocrinol Date: 2010-04-13 Impact factor: 43.330

3. The cellularity of offspring's adipose tissue is programmed by maternal nutritional manipulations.

Authors: Simon Lecoutre; Christophe Breton
Journal: Adipocyte Date: 2014-12-10 Impact factor: 4.534

4. White to beige conversion in PDE3B KO adipose tissue through activation of AMPK signaling and mitochondrial function.

Authors: Youn Wook Chung; Faiyaz Ahmad; Yan Tang; Steven C Hockman; Hyun Jung Kee; Karin Berger; Emilia Guirguis; Young Hun Choi; Dan M Schimel; Angel M Aponte; Sunhee Park; Eva Degerman; Vincent C Manganiello
Journal: Sci Rep Date: 2017-01-13 Impact factor: 4.379