| Literature DB >> 19339216 |
Matthieu Flourakis1, Natacha Prevarskaya.
Abstract
Prostate cancer is the second cancer-related cause of death. Nowadays, the aim of treatments is to decrease the effects of androgens on this organ. Unfortunately, over time, patients develop an androgen-independent cancer with a fatal outcome. The main features of late stage prostate cancer are an increased cell proliferation and apoptosis resistance. It is well known that calcium (Ca2+), a ubiquitous secondary messenger, is involved in several processes such as apoptosis and proliferation. In this mini review, we will focus on the changes in Ca2+ homeostasis of prostate cancer epithelial cells during prostate cancer evolution.Entities:
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Year: 2009 PMID： 19339216 DOI： 10.1016/j.bbamcr.2009.01.009
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002