BACKGROUND: Fat injection for soft tissue augmentation is a common procedure in plastic surgery. Because the limitation of fat injection is its resorption, understanding how different handling techniques affect adipocyte survival is crucial to optimizing long-term results. OBJECTIVE: In this study; we sought to determine the effect of aspiration and injection cannula diameters on adipocyte viability. METHODS: Fat aspiration samples were obtained from 6 female patients undergoing abdominoplasty. Viable adipocytes were counted at fat suspension, which was obtained with 2-, 3-, and 4-mm-diameter aspiration cannulas and injected with 1.6-, 2-, and 2.5-mm-diameter injection cannulas. RESULTS: A greater number of viable adipocytes were detected using a 4-mm-diameter aspiration cannula (419 x 10(4) cell/1 mL, P < .05) and a 2.5-mm-diameter injection cannula (410 x 10(4) cell/1 mL, P < .05). CONCLUSIONS: The use of wider-diameter cannulas can potentially improve fat graft survival and reduce fat graft resorption.
BACKGROUND: Fat injection for soft tissue augmentation is a common procedure in plastic surgery. Because the limitation of fat injection is its resorption, understanding how different handling techniques affect adipocyte survival is crucial to optimizing long-term results. OBJECTIVE: In this study; we sought to determine the effect of aspiration and injection cannula diameters on adipocyte viability. METHODS: Fat aspiration samples were obtained from 6 female patients undergoing abdominoplasty. Viable adipocytes were counted at fat suspension, which was obtained with 2-, 3-, and 4-mm-diameter aspiration cannulas and injected with 1.6-, 2-, and 2.5-mm-diameter injection cannulas. RESULTS: A greater number of viable adipocytes were detected using a 4-mm-diameter aspiration cannula (419 x 10(4) cell/1 mL, P < .05) and a 2.5-mm-diameter injection cannula (410 x 10(4) cell/1 mL, P < .05). CONCLUSIONS: The use of wider-diameter cannulas can potentially improve fat graft survival and reduce fat graft resorption.
Authors: Trent M Gause; Russell E Kling; Wesley N Sivak; Kacey G Marra; J Peter Rubin; Lauren E Kokai Journal: Adipocyte Date: 2014-12-10 Impact factor: 4.534
Authors: Matthew J Davis; Aurelia T Perdanasari; Amjed Abu-Ghname; Santiago R Gonzalez; Edward Chamata; Charalambos K Rammos; Sebastian J Winocour Journal: Semin Plast Surg Date: 2020-02-15 Impact factor: 2.314
Authors: Lukas Prantl; Andreas Eigenberger; Eva Brix; Sally Kempa; Magnus Baringer; Oliver Felthaus Journal: Cells Date: 2021-05-05 Impact factor: 6.600