| Literature DB >> 19337322 |
Abstract
Depletion of Ca(2+) from intracellular stores has long been known to signal to and activate plasma membrane 'store-operated' channels. We now learn that store depletion also controls the formation of cyclic AMP (cAMP) through the regulation of adenylyl cyclase (A-Cyclase). These findings substantially broaden the scope and biological significance of Ca(2+) store-regulated signalling.Entities:
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Year: 2009 PMID： 19337322 DOI： 10.1038/ncb0409-381
Source DB: PubMed Journal: Nat Cell Biol ISSN： 1465-7392 Impact factor: 28.824