Literature DB >> 19336604

Sirolimus and mTORC1: centre stage in the story of what makes muscles bigger?

Stuart M Phillips1.   

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Year:  2009        PMID: 19336604      PMCID: PMC2678207          DOI: 10.1113/jphysiol.2009.170738

Source DB:  PubMed          Journal:  J Physiol        ISSN: 0022-3751            Impact factor:   5.182


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  11 in total

1.  Changes in human muscle protein synthesis after resistance exercise.

Authors:  A Chesley; J D MacDougall; M A Tarnopolsky; S A Atkinson; K Smith
Journal:  J Appl Physiol (1985)       Date:  1992-10

2.  Resistance exercise increases AMPK activity and reduces 4E-BP1 phosphorylation and protein synthesis in human skeletal muscle.

Authors:  Hans C Dreyer; Satoshi Fujita; Jerson G Cadenas; David L Chinkes; Elena Volpi; Blake B Rasmussen
Journal:  J Physiol       Date:  2006-07-27       Impact factor: 5.182

3.  Resistance exercise increases muscle protein synthesis and translation of eukaryotic initiation factor 2Bepsilon mRNA in a mammalian target of rapamycin-dependent manner.

Authors:  Neil Kubica; Douglas R Bolster; Peter A Farrell; Scot R Kimball; Leonard S Jefferson
Journal:  J Biol Chem       Date:  2004-12-10       Impact factor: 5.157

4.  Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo.

Authors:  S C Bodine; T N Stitt; M Gonzalez; W O Kline; G L Stover; R Bauerlein; E Zlotchenko; A Scrimgeour; J C Lawrence; D J Glass; G D Yancopoulos
Journal:  Nat Cell Biol       Date:  2001-11       Impact factor: 28.824

5.  Maximal lengthening contractions increase p70 S6 kinase phosphorylation in human skeletal muscle in the absence of nutritional supply.

Authors:  Jörgen Eliasson; Thibault Elfegoun; Johnny Nilsson; Rickard Köhnke; Björn Ekblom; Eva Blomstrand
Journal:  Am J Physiol Endocrinol Metab       Date:  2006-07-11       Impact factor: 4.310

6.  Myofibrillar protein synthesis in young and old men.

Authors:  S Welle; C Thornton; R Jozefowicz; M Statt
Journal:  Am J Physiol       Date:  1993-05

7.  Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation.

Authors:  B T Navé; M Ouwens; D J Withers; D R Alessi; P R Shepherd
Journal:  Biochem J       Date:  1999-12-01       Impact factor: 3.857

8.  Resistance exercise decreases eIF2Bepsilon phosphorylation and potentiates the feeding-induced stimulation of p70S6K1 and rpS6 in young men.

Authors:  Elisa I Glover; Bryan R Oates; Jason E Tang; Daniel R Moore; Mark A Tarnopolsky; Stuart M Phillips
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2008-06-18       Impact factor: 3.619

9.  Rapamycin administration in humans blocks the contraction-induced increase in skeletal muscle protein synthesis.

Authors:  Micah J Drummond; Christopher S Fry; Erin L Glynn; Hans C Dreyer; Shaheen Dhanani; Kyle L Timmerman; Elena Volpi; Blake B Rasmussen
Journal:  J Physiol       Date:  2009-02-02       Impact factor: 5.182

10.  Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle.

Authors:  P L Greenhaff; L G Karagounis; N Peirce; E J Simpson; M Hazell; R Layfield; H Wackerhage; K Smith; P Atherton; A Selby; M J Rennie
Journal:  Am J Physiol Endocrinol Metab       Date:  2008-06-24       Impact factor: 4.310

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