Literature DB >> 19335172

Willingness to be circumcised for preventing HIV among Chinese men who have sex with men.

Yuhua Ruan1, Han-Zhu Qian, Dongliang Li, Wei Shi, Qingchun Li, Hongyuan Liang, Ye Yang, Fengji Luo, Sten H Vermund, Yiming Shao.   

Abstract

Male circumcision can reduce the risk of HIV acquisition among heterosexual men, but its effectiveness is uncertain in men who have sex with men (MSM). Additionally, its acceptability among Chinese men is unknown given a lack of history and cultural norms endorsing neonatal and adult circumcision. This study evaluated the willingness to participate in a clinical trial of circumcision among 328 Chinese MSM. Some 11.6% respondents reported having been circumcised, most of them due to a tight foreskin. Of 284 uncircumcised MSM, 16.9% said they were absolutely willing to participate, 26.4% were probably, 28.9% were probably not, and 27.8% were absolutely not; 81% said male circumcision would help maintain genital hygiene. The major motivators for willingness to participate included contribution to AIDS scientific research and getting free medical service. Men also had concerns about ineffectiveness of circumcision in reducing HIV/sexually transmitted infection (STI) risks and side effects of the surgery. Those who did not have a Beijing resident card (adjusted odds ratio [AOR], 1.99; 95% confidence interval [CI], 1.17-3.38), did not find sexual partners through the Internet (AOR, 2.13; 95% CI, 1.21-3.75), and were not concerned about the effectiveness of circumcision (AOR, 2.37; 95% CI, 1.34-4.19) were more likely to be willing to participate in a trial. The study suggests that circumcision is uncommon among Chinese MSM. Considerable community education will be needed in circumcision advocacy among MSM in China. A clinical trial for efficacy among MSM should be considered.

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Year:  2009        PMID: 19335172      PMCID: PMC2743100          DOI: 10.1089/apc.2008.0199

Source DB:  PubMed          Journal:  AIDS Patient Care STDS        ISSN: 1087-2914            Impact factor:   5.078


  25 in total

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Authors:  Charles C Lin; Xing Gao; Xiang-Sheng Chen; Qiang Chen; Myron S Cohen
Journal:  Sex Transm Dis       Date:  2006-12       Impact factor: 2.830

2.  High prevalence of sexually transmitted diseases among men who have sex with men in Jiangsu Province, China.

Authors:  Juan Jiang; Ningxiao Cao; Jinping Zhang; Qiang Xia; Xiangdong Gong; Huazhong Xue; Haitao Yang; Guocheng Zhang; Changgeng Shao
Journal:  Sex Transm Dis       Date:  2006-02       Impact factor: 2.830

3.  Circumcision and HIV prevention among men who have sex with men: no final word.

Authors:  Sten H Vermund; Han-Zhu Qian
Journal:  JAMA       Date:  2008-10-08       Impact factor: 56.272

4.  Potential bridges for HIV infection to men who have sex with men in Guangzhou, China.

Authors:  Qun He; Ye Wang; Peng Lin; Yongying Liu; Fang Yang; Xiaobing Fu; Yan Li; Baoshan Sun; Jie Li; Xixi Zhao; Jeffrey Mandel; Sheila Jain; Willi McFarland
Journal:  AIDS Behav       Date:  2006-06-27

5.  Potential HIV-1 target cells in the human penis.

Authors:  Scott G McCoombe; Roger V Short
Journal:  AIDS       Date:  2006-07-13       Impact factor: 4.177

6.  HIV-1 target cells in foreskins of African men with varying histories of sexually transmitted infections.

Authors:  Betty A Donoval; Alan L Landay; Stephen Moses; Kawango Agot; J O Ndinya-Achola; Edith A Nyagaya; Ian MacLean; Robert C Bailey
Journal:  Am J Clin Pathol       Date:  2006-03       Impact factor: 2.493

7.  Susceptibility to human immunodeficiency virus-1 infection of human foreskin and cervical tissue grown in explant culture.

Authors:  Bruce K Patterson; Alan Landay; Joan N Siegel; Zareefa Flener; Dennis Pessis; Antonio Chaviano; Robert C Bailey
Journal:  Am J Pathol       Date:  2002-09       Impact factor: 4.307

8.  Randomized, controlled intervention trial of male circumcision for reduction of HIV infection risk: the ANRS 1265 Trial.

Authors:  Bertran Auvert; Dirk Taljaard; Emmanuel Lagarde; Joëlle Sobngwi-Tambekou; Rémi Sitta; Adrian Puren
Journal:  PLoS Med       Date:  2005-10-25       Impact factor: 11.069

9.  Male circumcision, religion, and infectious diseases: an ecologic analysis of 118 developing countries.

Authors:  Paul K Drain; Daniel T Halperin; James P Hughes; Jeffrey D Klausner; Robert C Bailey
Journal:  BMC Infect Dis       Date:  2006-11-30       Impact factor: 3.090

Review 10.  Male circumcision and risk of syphilis, chancroid, and genital herpes: a systematic review and meta-analysis.

Authors:  H A Weiss; S L Thomas; S K Munabi; R J Hayes
Journal:  Sex Transm Infect       Date:  2006-04       Impact factor: 3.519

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  24 in total

1.  The feasibility and acceptability of male circumcision among men, women, and health providers of the Altagracia Province, Dominican Republic.

Authors:  Maximo O Brito; Maximiliano Luna; Robert C Bailey
Journal:  AIDS Care       Date:  2010-12

2.  Modeling economic and epidemiological impact of voluntary medical male circumcision among men who have sex with men in Beijing, China.

Authors:  Chen Zhang; David F Penson; Han-Zhu Qian; Glenn F Webb; Jie Lou; Brian E Shephard; Yu Liu; Sten H Vermund
Journal:  Int J STD AIDS       Date:  2019-03-19       Impact factor: 1.359

Review 3.  Interventions to improve the HIV continuum of care in China.

Authors:  Xiangjun Zhang; Na Wang; Sten H Vermund; Huachun Zou; Xianhong Li; Fujie Zhang; Han-Zhu Qian
Journal:  Curr HIV/AIDS Rep       Date:  2019-12       Impact factor: 5.071

4.  Dynamic mathematical models of HIV/AIDS transmission in China.

Authors:  Jun-jie Wang; Kathleen Heather Reilly; Jing Luo; Chun-peng Zang; Ning Wang
Journal:  Chin Med J (Engl)       Date:  2010-08-05       Impact factor: 2.628

5.  Acceptability of male circumcision for the prevention of HIV/AIDS in the Dominican Republic.

Authors:  Maximo O Brito; Lilliam M Caso; Hannabell Balbuena; Robert C Bailey
Journal:  PLoS One       Date:  2009-11-02       Impact factor: 3.240

6.  Popular perceptions of circumcision among Colombian men who have sex with men.

Authors:  Felisa A Gonzales; Maria Cecilia Zea; Carol A Reisen; Fernanda T Bianchi; Carlos Fabian Betancourt Rodríguez; Marcela Aguilar Pardo; Paul J Poppen
Journal:  Cult Health Sex       Date:  2012-08-23

Review 7.  Behavioral aspects of male circumcision for the prevention of HIV infection.

Authors:  Lisa Eaton; Seth C Kalichman
Journal:  Curr HIV/AIDS Rep       Date:  2009-11       Impact factor: 5.071

8.  Lower HIV Risk Among Circumcised Men Who Have Sex With Men in China: Interaction With Anal Sex Role in a Cross-Sectional Study.

Authors:  Han-Zhu Qian; Yuhua Ruan; Yu Liu; Douglas F Milam; Hans M L Spiegel; Lu Yin; Dongliang Li; Bryan E Shepherd; Yiming Shao; Sten H Vermund
Journal:  J Acquir Immune Defic Syndr       Date:  2016-04-01       Impact factor: 3.731

9.  Acceptance of male circumcision among male rural-to-urban migrants in western China.

Authors:  Junjun Jiang; Jiegang Huang; Xiaobo Yang; Li Ye; Bo Wei; Wei Deng; Suosu Wei; Bo Qin; Halmurat Upur; Chaohui Zhong; Qianqiu Wang; Qian Wang; Yuhua Ruan; Fumei Wei; Na Xu; Peiyan Xie; Hao Liang
Journal:  AIDS Res Hum Retroviruses       Date:  2013-09-04       Impact factor: 2.205

10.  Circumcision to prevent HIV and other sexually transmitted infections in men who have sex with men: a systematic review and meta-analysis of global data.

Authors:  Tanwei Yuan; Thomas Fitzpatrick; Nai-Ying Ko; Yong Cai; Yingqing Chen; Jin Zhao; Linghua Li; Junjie Xu; Jing Gu; Jinghua Li; Chun Hao; Zhengrong Yang; Weiping Cai; Chien-Yu Cheng; Zhenzhou Luo; Kechun Zhang; Guohui Wu; Xiaojun Meng; Andrew E Grulich; Yuantao Hao; Huachun Zou
Journal:  Lancet Glob Health       Date:  2019-04       Impact factor: 26.763

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