| Literature DB >> 19334028 |
Yan Xu1, Yuta Suzuki, Makoto Komiyama.
Abstract
A trap that closes with a "click": The copper-catalyzed azide-alkyne cycloaddition can occur in different G-quadruplex structures (see scheme). The species trapped by the click reaction can then be separated and analyzed. By using this approach, a DNA-RNA hybrid-type G-quadruplex structure formed by human telomeric DNA and RNA sequences was detected.Entities:
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Year: 2009 PMID: 19334028 DOI: 10.1002/anie.200806306
Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN: 1433-7851 Impact factor: 15.336