BACKGROUND: Extrauterine endometrial stromal sarcoma (ESS) is a rare neoplasm. Little is known about its pathophysiology or best treatment approach. CASE: We are describing a case of extrauterine ESS in a 70-year-old woman on hormone replacement therapy and with a history of endometriosis. We also present a brief review of the literature on ESS and its relationship to endometriosis and hormonal therapy. CONCLUSIONS: Complete resection should remain the treatment of choice for ESS. Unresectable or metastatic low-grade ESS may respond well to progestin therapy, but outcomes of high-grade ESS tend to be poor.
BACKGROUND: Extrauterine endometrial stromal sarcoma (ESS) is a rare neoplasm. Little is known about its pathophysiology or best treatment approach. CASE: We are describing a case of extrauterine ESS in a 70-year-old woman on hormone replacement therapy and with a history of endometriosis. We also present a brief review of the literature on ESS and its relationship to endometriosis and hormonal therapy. CONCLUSIONS: Complete resection should remain the treatment of choice for ESS. Unresectable or metastatic low-grade ESS may respond well to progestin therapy, but outcomes of high-grade ESS tend to be poor.
Authors: Daniel Pink; Tanja Lindner; Alicia Mrozek; Albrecht Kretzschmar; Peter C Thuss-Patience; Bernd Dörken; Peter Reichardt Journal: Gynecol Oncol Date: 2005-12-20 Impact factor: 5.482
Authors: D Benjamin Christie; J Daniel Day; Amy B Moore; Jason R Chapman; Don K Nakayama; Arnold M Conforti Journal: Am Surg Date: 2008-08 Impact factor: 0.688