OBJECTIVE: To examine the long-term relationship between sleep duration and type 2 diabetes or impaired glucose tolerance (IGT). METHODS: Body composition measurements and self-reported sleep duration were determined in a longitudinal sample of 276 individuals aged 21 to 64 years followed for a mean of 6 years. Risk factors of type 2 diabetes/IGT over the follow-up were determined and relative risks (RRs) calculated for the development of type 2 diabetes/IGT by sleep duration group. RESULTS: Independent risk factors of type 2 diabetes/IGT over the follow-up included age, obesity, sleep duration, and glucose/insulin homeostasis indicators. Using adults with 7-8h of sleep as a reference, the adjusted RR for the development of type 2 diabetes/IGT was 2.78 (1.61-4.12) for those with 6h of sleep and 2.54 (1.42-3.53) for those with 9h of sleep. These elevated RRs remained significant after adjustment for body mass index, waist circumference or percent body fat. CONCLUSION: Short and long sleeping times are associated with a higher risk of developing type 2 diabetes/IGT, independent of several covariates. These results suggest that sleep duration may represent a novel risk factor for type 2 diabetes/IGT.
OBJECTIVE: To examine the long-term relationship between sleep duration and type 2 diabetes or impaired glucose tolerance (IGT). METHODS: Body composition measurements and self-reported sleep duration were determined in a longitudinal sample of 276 individuals aged 21 to 64 years followed for a mean of 6 years. Risk factors of type 2 diabetes/IGT over the follow-up were determined and relative risks (RRs) calculated for the development of type 2 diabetes/IGT by sleep duration group. RESULTS: Independent risk factors of type 2 diabetes/IGT over the follow-up included age, obesity, sleep duration, and glucose/insulin homeostasis indicators. Using adults with 7-8h of sleep as a reference, the adjusted RR for the development of type 2 diabetes/IGT was 2.78 (1.61-4.12) for those with 6h of sleep and 2.54 (1.42-3.53) for those with 9h of sleep. These elevated RRs remained significant after adjustment for body mass index, waist circumference or percent body fat. CONCLUSION: Short and long sleeping times are associated with a higher risk of developing type 2 diabetes/IGT, independent of several covariates. These results suggest that sleep duration may represent a novel risk factor for type 2 diabetes/IGT.
Authors: Jonathan Lee; Tanvir C Turin; David D M Nicholl; Sofia B Ahmed; Andrea H S Loewen; Brenda R Hemmelgarn; Abul K Azad; Patrick J Hanly Journal: Sleep Breath Date: 2014-11-05 Impact factor: 2.816
Authors: Subhajit Chakravorty; H Y Katy Siu; Linden Lalley-Chareczko; Gregory K Brown; James C Findley; Michael L Perlis; Michael A Grandner Journal: Prim Care Companion CNS Disord Date: 2015-12-31
Authors: Jennifer Schwartz; Matthew A Allison; Sonia Ancoli-Israel; Melbourne F Hovell; Ruth E Patterson; Loki Natarajan; Simon J Marshall; Igor Grant Journal: Arch Gerontol Geriatr Date: 2013-03-20 Impact factor: 3.250