Literature DB >> 19332371

New Labdane diterpenes as intestinal alpha-glucosidase inhibitor from antihyperglycemic extract of Hedychium spicatum (Ham. Ex Smith) rhizomes.

P Prabhakar Reddy1, Ashok K Tiwari, R Ranga Rao, K Madhusudhana, V Rama Subba Rao, Amtul Z Ali, K Suresh Babu, J Madhusudana Rao.   

Abstract

Phytochemical investigation of antihyperglycemic extract of rhizomes of Hedychium spicatum led to the isolation of two new labdane type diterpenes 2, 3 along with seven known compounds (1, 4-9). Their structures were established on the basis of NMR (1D and 2D) and mass spectroscopic analysis. The new compound 2 displayed strong intestinal alpha-glucosidase inhibitory activity. Other compounds also displayed varying degree of intestinal alpha-glucosidase inhibitory potential.

Entities:  

Mesh：

Substances：

Year:  2009        PMID： 19332371     DOI： 10.1016/j.bmcl.2009.03.045

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  5 in total

1.  Inhibitory potential of omega-3 fatty and fenugreek essential oil on key enzymes of carbohydrate-digestion and hypertension in diabetes rats.

Authors:  Khaled Hamden; Henda Keskes; Sahla Belhaj; Kais Mnafgui; Abdelfattah Feki; Noureddine Allouche
Journal:  Lipids Health Dis       Date:  2011-12-05       Impact factor: 3.876

2.  A pharmacological appraisal of medicinal plants with antidiabetic potential.

Authors:  Vasim Khan; Abul Kalam Najmi; Mohd Akhtar; Mohd Aqil; Mohd Mujeeb; K K Pillai
Journal:  J Pharm Bioallied Sci       Date:  2012-01

3.  Momilactones A and B Are α-Amylase and α-Glucosidase Inhibitors.

Authors:  Nguyen Van Quan; Hoang-Dung Tran; Tran Dang Xuan; Ateeque Ahmad; Tran Dang Dat; Tran Dang Khanh; Rolf Teschke
Journal:  Molecules       Date:  2019-01-29       Impact factor: 4.411

Review 4.  Alpha Glucosidase Inhibitory Activities of Plants with Focus on Common Vegetables.

Authors:  Samuel Tilahun Assefa; Eun-Young Yang; Soo-Young Chae; Mihye Song; Jundae Lee; Myeong-Cheoul Cho; Seonghoe Jang
Journal:  Plants (Basel)       Date:  2019-12-18

5.  α-Glucosidase and Pancreatic Lipase Inhibitory Activities of Diterpenes from Indian Mango Ginger (Curcuma amada Roxb.) and Its Derivatives.

Authors:  Yuri Yoshioka; Naori Yoshimura; Shinichi Matsumura; Hiroto Wada; Maya Hoshino; Shouhei Makino; Masanori Morimoto
Journal:  Molecules       Date:  2019-11-10       Impact factor: 4.411
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.