| Literature DB >> 19331352 |
Ken S Feldman1, Matthew D Fodor.
Abstract
The sponge-derived alkaloid dibromoagelaspongin was prepared from a dihydrooroidin derivative by exploiting the Pummerer reaction twice in succession. Oxidative cyclization of the substrate's pyrrole-2-carboxamide function into the imidazole moiety was achieved in a regiospecific manner to establish both C-N bonds to C(6) of the target.Entities:
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Year: 2009 PMID： 19331352 DOI： 10.1021/jo900283g
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354