Literature DB >> 19330028

Analysis of the matrix metalloproteinase family reveals that MMP8 is often mutated in melanoma.

Lavanya H Palavalli1, Todd D Prickett, John R Wunderlich, Xiaomu Wei, Allison S Burrell, Patricia Porter-Gill, Sean Davis, Chenwei Wang, Julia C Cronin, Neena S Agrawal, Jimmy C Lin, Wendy Westbroek, Shelley Hoogstraten-Miller, Alfredo A Molinolo, Patricia Fetsch, Armando C Filie, Michael P O'Connell, Carolyn E Banister, Jason D Howard, Phillip Buckhaults, Ashani T Weeraratna, Lawrence C Brody, Steven A Rosenberg, Yardena Samuels.   

Abstract

A mutational analysis of the matrix metalloproteinase (MMP) gene family in human melanoma identified somatic mutations in 23% of melanomas. Five mutations in one of the most commonly mutated genes, MMP8, reduced MMP enzyme activity. Expression of wild-type but not mutant MMP8 in human melanoma cells inhibited growth on soft agar in vitro and tumor formation in vivo, suggesting that wild-type MMP-8 has the ability to inhibit melanoma progression.

Entities:  

Mesh：

Substances：

Year:  2009        PMID： 19330028      PMCID： PMC2748394          DOI： 10.1038/ng.340

Source DB:  PubMed          Journal:  Nat Genet        ISSN： 1061-4036            Impact factor:   38.330


  14 in total

Review 1.  New functions for the matrix metalloproteinases in cancer progression.

Authors:  Mikala Egeblad; Zena Werb
Journal:  Nat Rev Cancer       Date:  2002-03       Impact factor: 60.716

Review 2.  Matrix metalloproteinases: a tail of a frog that became a prince.

Authors:  Constance E Brinckerhoff; Lynn M Matrisian
Journal:  Nat Rev Mol Cell Biol       Date:  2002-03       Impact factor: 94.444

Review 3.  p53: puzzle and paradigm.

Authors:  L J Ko; C Prives
Journal:  Genes Dev       Date:  1996-05-01       Impact factor: 11.361

4.  Analysis of host- and tumor-derived proteinases using a custom dual species microarray reveals a protective role for stromal matrix metalloproteinase-12 in non-small cell lung cancer.

Authors:  Heath B Acuff; Mark Sinnamon; Barbara Fingleton; Braden Boone; Shawn E Levy; Xiwu Chen; Ambra Pozzi; David P Carbone; Donald R Schwartz; Kamiar Moin; Bonnie F Sloane; Lynn M Matrisian
Journal:  Cancer Res       Date:  2006-08-15       Impact factor: 12.701

5.  The melanocyte differentiation program predisposes to metastasis after neoplastic transformation.

Authors:  Piyush B Gupta; Charlotte Kuperwasser; Jean-Philippe Brunet; Sridhar Ramaswamy; Wen-Lin Kuo; Joe W Gray; Stephen P Naber; Robert A Weinberg
Journal:  Nat Genet       Date:  2005-09-04       Impact factor: 38.330

6.  Mouse macrophage metalloelastase gene transfer into a murine melanoma suppresses primary tumor growth by halting angiogenesis.

Authors:  M J Gorrin-Rivas; S Arii; M Furutani; M Mizumoto; A Mori; K Hanaki; M Maeda; H Furuyama; Y Kondo; M Imamura
Journal:  Clin Cancer Res       Date:  2000-05       Impact factor: 12.531

Review 7.  Matrix metalloproteinase inhibitors and cancer: trials and tribulations.

Authors:  Lisa M Coussens; Barbara Fingleton; Lynn M Matrisian
Journal:  Science       Date:  2002-03-29       Impact factor: 47.728

8.  Loss of collagenase-2 confers increased skin tumor susceptibility to male mice.

Authors:  Milagros Balbín; Antonio Fueyo; Angus M Tester; Alberto M Pendás; Ana S Pitiot; Aurora Astudillo; Christopher M Overall; Steven D Shapiro; Carlos López-Otín
Journal:  Nat Genet       Date:  2003-09-28       Impact factor: 38.330

Review 9.  Matrix metalloproteinases and tumor progression.

Authors:  José M P Freije; Milagros Balbín; Alberto M Pendás; Luis M Sánchez; Xose S Puente; Carlos López-Otín
Journal:  Adv Exp Med Biol       Date:  2003       Impact factor: 2.622

10.  Matrix metalloproteinase-8 functions as a metastasis suppressor through modulation of tumor cell adhesion and invasion.

Authors:  Ana Gutiérrez-Fernández; Antonio Fueyo; Alicia R Folgueras; Cecilia Garabaya; Caroline J Pennington; Simon Pilgrim; Dylan R Edwards; Deborah L Holliday; J Louise Jones; Paul N Span; Fred C G J Sweep; Xose S Puente; Carlos López-Otín
Journal:  Cancer Res       Date:  2008-04-15       Impact factor: 12.701
View more
  74 in total

Review 1.  Delving into somatic variation in sporadic melanoma.

Authors:  Vijay Walia; Euphemia W Mu; Jimmy C Lin; Yardena Samuels
Journal:  Pigment Cell Melanoma Res       Date:  2012-02-13       Impact factor: 4.693

Review 2.  Metzincin proteases and their inhibitors: foes or friends in nervous system physiology?

Authors:  Santiago Rivera; Michel Khrestchatisky; Leszek Kaczmarek; Gary A Rosenberg; Diane M Jaworski
Journal:  J Neurosci       Date:  2010-11-17       Impact factor: 6.167

3.  Variability in melanoma metalloproteinase expression profiling.

Authors:  Orsi Giricz; Janelle L Lauer; Gregg B Fields
Journal:  J Biomol Tech       Date:  2010-12

4.  Exome sequencing identifies GRIN2A as frequently mutated in melanoma.

Authors:  Xiaomu Wei; Vijay Walia; Jimmy C Lin; Jamie K Teer; Todd D Prickett; Jared Gartner; Sean Davis; Katherine Stemke-Hale; Michael A Davies; Jeffrey E Gershenwald; William Robinson; Steven Robinson; Steven A Rosenberg; Yardena Samuels
Journal:  Nat Genet       Date:  2011-04-15       Impact factor: 38.330

5.  Whole-genome sequencing identifies a recurrent functional synonymous mutation in melanoma.

Authors:  Jared J Gartner; Stephen C J Parker; Todd D Prickett; Ken Dutton-Regester; Michael L Stitzel; Jimmy C Lin; Sean Davis; Vijaya L Simhadri; Sujata Jha; Nobuko Katagiri; Valer Gotea; Jamie K Teer; Xiaomu Wei; Mario A Morken; Umesh K Bhanot; Guo Chen; Laura L Elnitski; Michael A Davies; Jeffrey E Gershenwald; Hannah Carter; Rachel Karchin; William Robinson; Steven Robinson; Steven A Rosenberg; Francis S Collins; Giovanni Parmigiani; Anton A Komar; Chava Kimchi-Sarfaty; Nicholas K Hayward; Elliott H Margulies; Yardena Samuels
Journal:  Proc Natl Acad Sci U S A       Date:  2013-07-30       Impact factor: 11.205

6.  Mutational and functional analysis reveals ADAMTS18 metalloproteinase as a novel driver in melanoma.

Authors:  Xiaomu Wei; Todd D Prickett; Cristina G Viloria; Alfredo Molinolo; Jimmy C Lin; Isabel Cardenas-Navia; Pedro Cruz; Steven A Rosenberg; Michael A Davies; Jeffrey E Gershenwald; Carlos López-Otín; Yardena Samuels
Journal:  Mol Cancer Res       Date:  2010-10-13       Impact factor: 5.852

7.  Targeting angiogenesis in melanoma: prospects for the future.

Authors:  P G Corrie; B Basu; K Ahmad Zaki
Journal:  Ther Adv Med Oncol       Date:  2010-11       Impact factor: 8.168

Review 8.  Exploiting the curative potential of adoptive T-cell therapy for cancer.

Authors:  Christian S Hinrichs; Steven A Rosenberg
Journal:  Immunol Rev       Date:  2014-01       Impact factor: 12.988

9.  A comprehensive catalogue of somatic mutations from a human cancer genome.

Authors:  Erin D Pleasance; R Keira Cheetham; Philip J Stephens; David J McBride; Sean J Humphray; Chris D Greenman; Ignacio Varela; Meng-Lay Lin; Gonzalo R Ordóñez; Graham R Bignell; Kai Ye; Julie Alipaz; Markus J Bauer; David Beare; Adam Butler; Richard J Carter; Lina Chen; Anthony J Cox; Sarah Edkins; Paula I Kokko-Gonzales; Niall A Gormley; Russell J Grocock; Christian D Haudenschild; Matthew M Hims; Terena James; Mingming Jia; Zoya Kingsbury; Catherine Leroy; John Marshall; Andrew Menzies; Laura J Mudie; Zemin Ning; Tom Royce; Ole B Schulz-Trieglaff; Anastassia Spiridou; Lucy A Stebbings; Lukasz Szajkowski; Jon Teague; David Williamson; Lynda Chin; Mark T Ross; Peter J Campbell; David R Bentley; P Andrew Futreal; Michael R Stratton
Journal:  Nature       Date:  2009-12-16       Impact factor: 49.962

10.  Upregulation of MMP-2 by HMGA1 promotes transformation in undifferentiated, large-cell lung cancer.

Authors:  Joelle Hillion; Lisa J Wood; Mita Mukherjee; Raka Bhattacharya; Francescopaolo Di Cello; Jeanne Kowalski; Ossama Elbahloul; Jodi Segal; John Poirier; Charles M Rudin; Surajit Dhara; Amy Belton; Biju Joseph; Stanley Zucker; Linda M S Resar
Journal:  Mol Cancer Res       Date:  2009-11-10       Impact factor: 5.852
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.