Literature DB >> 19329917

Should octogenarians be denied access to surgery for acute type A aortic dissection?

A Piccardo1, T Regesta, S Pansini, G Concistrè, A Dell'Aquila, F Scarano, L Martinelli, G Passerone.   

Abstract

AIM: Outcomes after surgery for acute type A aortic dissection in the octogenarian are controversial. To analyze this issue further, the authors reviewed their experience in the hope of finding ways to improve results in these high-risk patients.
METHODS: Between April 1990 and November 2006, 319 consecutive patients underwent emergency surgery for acute type A aortic dissection at the San Martino University Hospital of Genoa (Italy). Among them, 23 (7%) patients were aged 80 years or older (mean age 82 years, range 80 to 86 years) and represent the study population. On admission 7 patients (30%) had preoperative shock, 1 needed cardiopulmonary resuscitation, 7 (30%) had a neurological deficit, 2 (9%) had acute renal failure. Deep hypothermic circulatory arrest was performed in 19 patients (83%). Surgical procedures included isolated replacement of the ascending aorta in all patients associated with root replacement in 2 (9%) and total aortic arch replacement in 5 (22%). Median follow up was 4.1 years (range 3 to 83 months).
RESULTS: Hospital mortality was 61% (14 of 23 patients). Late mortality was 11% (1 of 9 survivors). Stepwise logistic regression identified the extension of surgery to the arch as independent risk factors for hospital death. Fourteen patients (61%) had 1 or more postoperative complications. Overall survival was 39+/-10% and 33+/-10% after 1 and 5 years respectively.
CONCLUSIONS: Surgery for acute type A aortic dissection in the octogenarian shows high hospital mortality but satisfactory long-term survival among discharged patients. A less aggressive approach should increase the outcomes of surgically managed patients.

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Year:  2009        PMID: 19329917

Source DB:  PubMed          Journal:  J Cardiovasc Surg (Torino)        ISSN: 0021-9509            Impact factor:   1.888


  8 in total

Review 1.  Emergent aortic surgery in octogenarians: is the advanced age a contraindication?

Authors:  Mario Castaño; Javier Gualis; Jose M Martínez-Comendador; Elio Martín; Pasquale Maiorano; Laura Castillo
Journal:  J Thorac Dis       Date:  2017-05       Impact factor: 2.895

2.  [German Registry for Acute Aortic Dissection Type A (GERAADA): initial results].

Authors:  L O Conzelmann; T Krüger; I Hoffmann; B Rylski; J Easo; M Oezkur; K Kallenbach; O Dapunt; M Karck; E Weigang
Journal:  Herz       Date:  2011-09       Impact factor: 1.443

3.  Stable haemodynamics associated with no significant electrocardiogram abnormalities is a good prognostic factor of survival for acute type A aortic dissection repair.

Authors:  Tsu-Ming Chien; Wei-Yu Li; Hao Wen; Jiann-Woei Huang; Chong-Chao Hsieh; Huai-Min Chen; Chaw-Chi Chiu; Ying-Fu Chen
Journal:  Interact Cardiovasc Thorac Surg       Date:  2012-11-19

Review 4.  Aortic dissections in the elderly: ethical dilemmas of treatment.

Authors:  Anthony L Estrera; Hazim J Safi
Journal:  Tex Heart Inst J       Date:  2012

5.  Prognostic Implications of Acute Renal Failure after Surgery for Type A Acute Aortic Dissection.

Authors:  Fabrizio Sansone; Alessandro Morgante; Fabrizio Ceresa; Giovanni Salamone; Francesco Patanè
Journal:  Aorta (Stamford)       Date:  2015-06-01

6.  Outcomes in the current surgical era following operative repair of acute Type A aortic dissection in the elderly: a single-institutional experience.

Authors:  Ahmet Kilic; Richard Tang; Bryan A Whitson; John H Sirak; Chittoor B Sai-Sudhakar; Juan Crestanello; Robert S D Higgins
Journal:  Interact Cardiovasc Thorac Surg       Date:  2013-04-05

7.  Age, sex, and contemporary outcomes in surgical repair of type A aortic dissection: Insights from the National Inpatient Sample.

Authors:  Michael A Catalano; Tania Mamdouhi; Stevan Pupovac; Kevin F Kennedy; Derek R Brinster; Alan Hartman; Pey-Jen Yu
Journal:  JTCVS Open       Date:  2022-06-23

8.  Outcomes of Acute Aortic Dissection Surgery in Octogenarians.

Authors:  Ming-En Hsu; An-Hsun Chou; Yu-Ting Cheng; Hsiu-An Lee; Kuo-Sheng Liu; Dong-Yi Chen; Victor Chien-Chia Wu; Pao-Hsien Chu; Tien-Hsing Chen; Shao-Wei Chen
Journal:  J Am Heart Assoc       Date:  2020-09-11       Impact factor: 5.501

  8 in total

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