BACKGROUND/AIMS: Opisthorchiasis, a helminthic infection occurring endemically in certain areas of Europe and Asia is caused by parasites of the class trematoda. Failure to treat or a significant delay in the institution of an adequate therapy can lead to considerable complications in the further course of the disease. CASE: A 56-year-old patient diagnosed with primary biliary cirrhosis (PBC) with Child-Pugh stage B was referred to our surgical department from a peripheral hospital for liver transplantation. She had spent 50 years of her life in Kazakhstan. RESULTS: As the treatment of choice, orthotopic liver transplantation was carried out. The routine postoperative pathological analysis of the explanted liver showed the histological picture of opisthorchiasis. Further work-up in an effort to confirm the histological diagnosis was repeatedly negative. CONCLUSIONS: Opisthorchiasis should always be a diagnostic consideration in an unclear case of chronic liver disease especially in patients living in endemic areas.
BACKGROUND/AIMS: Opisthorchiasis, a helminthic infection occurring endemically in certain areas of Europe and Asia is caused by parasites of the class trematoda. Failure to treat or a significant delay in the institution of an adequate therapy can lead to considerable complications in the further course of the disease. CASE: A 56-year-old patient diagnosed with primary biliary cirrhosis (PBC) with Child-Pugh stage B was referred to our surgical department from a peripheral hospital for liver transplantation. She had spent 50 years of her life in Kazakhstan. RESULTS: As the treatment of choice, orthotopic liver transplantation was carried out. The routine postoperative pathological analysis of the explanted liver showed the histological picture of opisthorchiasis. Further work-up in an effort to confirm the histological diagnosis was repeatedly negative. CONCLUSIONS: Opisthorchiasis should always be a diagnostic consideration in an unclear case of chronic liver disease especially in patients living in endemic areas.
Authors: Alexandra G Pershina; Vladimir V Ivanov; Lina V Efimova; Oleg B Shevelev; Sergey V Vtorushin; Tatjana V Perevozchikova; Alexey E Sazonov; Ludmila M Ogorodova Journal: PLoS Negl Trop Dis Date: 2017-07-14
Authors: Alexander M Demin; Alexandra G Pershina; Vladimir V Ivanov; Kseniya V Nevskaya; Oleg B Shevelev; Artyom S Minin; Iliya V Byzov; Alexey E Sazonov; Victor P Krasnov; Ludmila M Ogorodova Journal: Int J Nanomedicine Date: 2016-09-06