Literature DB >> 19328750

Proteomic Helicobacter pylori biomarkers discriminating between duodenal ulcer and gastric cancer.

Ghalia Khoder1, Yoshio Yamaoka, Jean-Louis Fauchère, Christophe Burucoa, Christo Atanassov.   

Abstract

Protein patterns of 129 Helicobacter pylori strains isolated from Korean and Colombian patients suffering from duodenal ulcer or gastric cancer were analyzed by the high-throughput methodology SELDI-TOF-MS. Eighteen statistically significant candidate biomarkers discriminating between the two clinical outcomes were selected by using the Mann-Whitney test. Three biomarker proteins were purified and identified as a neutrophil-activating protein NapA (HU HPAG1_0821), a RNA-binding protein (HPAG1_0813), and a DNA-binding histone-like protein HU, respectively (jhp0228). These novel biomarkers can be used for development of diagnostic assays predicting the evolution to gastric cancer in H. pylori-infected patients.

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Year:  2009        PMID： 19328750      PMCID： PMC4088323          DOI： 10.1016/j.jchromb.2009.03.003

Source DB:  PubMed          Journal:  J Chromatogr B Analyt Technol Biomed Life Sci        ISSN： 1570-0232            Impact factor:   3.205


  30 in total

1.  The SELDI-TOF MS approach to proteomics: protein profiling and biomarker identification.

Authors:  Haleem J Issaq; Timothy D Veenstra; Thomas P Conrads; Donna Felschow
Journal:  Biochem Biophys Res Commun       Date:  2002-04-05       Impact factor: 3.575

2.  Discrimination between cases of duodenal ulcer and gastritis on the basis of putative virulence factors of Helicobacter pylori.

Authors:  Yoshio Yamaoka; Julianne Souchek; Stefan Odenbreit; Rainer Haas; Anna Arnqvist; Thomas Borén; Tadashi Kodama; Michael S Osato; Oscar Gutierrez; Jong G Kim; David Y Graham
Journal:  J Clin Microbiol       Date:  2002-06       Impact factor: 5.948

3.  Immunoproteomics.

Authors:  Alexander Krah; Peter R Jungblut
Journal:  Methods Mol Med       Date:  2004

4.  Novel antigens of Helicobacter pylori correspond to ulcer-related antibody pattern of sera from infected patients.

Authors:  Christo Atanassov; Leon Pezennec; Jacques d'Alayer; Ghislaine Grollier; Bertrand Picard; Jean-Louis Fauchère
Journal:  J Clin Microbiol       Date:  2002-02       Impact factor: 5.948

5.  Helicobacter pylori infection and the development of gastric cancer.

Authors:  N Uemura; S Okamoto; S Yamamoto; N Matsumura; S Yamaguchi; M Yamakido; K Taniyama; N Sasaki; R J Schlemper
Journal:  N Engl J Med       Date:  2001-09-13       Impact factor: 91.245

6.  Potential for proteomic profiling of Helicobacter pylori and other Helicobacter spp. using a ProteinChip array.

Authors:  Sean O Hynes; Jim McGuire; Torkel Wadström
Journal:  FEMS Immunol Med Microbiol       Date:  2003-05-25

7.  Substrate specificity of Helicobacter pylori histone-like HU protein is determined by insufficient stabilization of DNA flexure points.

Authors:  Christina Chen; Sharmistha Ghosh; Anne Grove
Journal:  Biochem J       Date:  2004-10-15       Impact factor: 3.857

8.  Helicobacter pylori virulence factors--one part of a big picture.

Authors:  Michael Höcker; Peter Hohenberger
Journal:  Lancet       Date:  2003-10-11       Impact factor: 79.321

9.  Proteins released by Helicobacter pylori in vitro.

Authors:  Nayoung Kim; David L Weeks; Jai Moo Shin; David R Scott; Mary K Young; George Sachs
Journal:  J Bacteriol       Date:  2002-11       Impact factor: 3.490

10.  Identification of candidate antigens for serologic detection of Helicobacter pylori-infected patients with gastric carcinoma.

Authors:  Alexander Krah; Stephan Miehlke; Klaus-Peter Pleissner; Ursula Zimny-Arndt; Christian Kirsch; Norbert Lehn; Thomas F Meyer; Peter R Jungblut; Toni Aebischer
Journal:  Int J Cancer       Date:  2004-01-20       Impact factor: 7.396
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  8 in total

1.  A histone-like protein of Helicobacter pylori protects DNA from stress damage and aids host colonization.

Authors:  Ge Wang; Leja F Lo; Robert J Maier
Journal:  DNA Repair (Amst)       Date:  2012-07-08

2.  Differential proteomics of Helicobacter pylori associated with autoimmune atrophic gastritis.

Authors:  Ombretta Repetto; Stefania Zanussi; Mariateresa Casarotto; Vincenzo Canzonieri; Paolo De Paoli; Renato Cannizzaro; Valli De Re
Journal:  Mol Med       Date:  2014-02-28       Impact factor: 6.354

3.  Complexomics study of two Helicobacter pylori strains of two pathological origins: potential targets for vaccine development and new insight in bacteria metabolism.

Authors:  Cédric Bernarde; Philippe Lehours; Jean-Paul Lasserre; Michel Castroviejo; Marc Bonneu; Francis Mégraud; Armelle Ménard
Journal:  Mol Cell Proteomics       Date:  2010-07-07       Impact factor: 5.911

4.  A novel DNA-binding protein plays an important role in Helicobacter pylori stress tolerance and survival in the host.

Authors:  Ge Wang; Robert J Maier
Journal:  J Bacteriol       Date:  2014-12-22       Impact factor: 3.490

5.  Comparative genomics and proteomics of Helicobacter mustelae, an ulcerogenic and carcinogenic gastric pathogen.

Authors:  Paul W O'Toole; William J Snelling; Carlos Canchaya; Brian M Forde; Kim R Hardie; Christine Josenhans; Robert Lj Graham; Geoff McMullan; Julian Parkhill; Eugenio Belda; Stephen D Bentley
Journal:  BMC Genomics       Date:  2010-03-10       Impact factor: 3.969

Review 6.  Helicobacter pylori neutrophil-activating protein: from molecular pathogenesis to clinical applications.

Authors:  Hua-Wen Fu
Journal:  World J Gastroenterol       Date:  2014-05-14       Impact factor: 5.742

7.  Candidate proteomic biomarkers for three genogroups of the swine pathogen Streptococcus suis serotype 2.

Authors:  Christo Atanassov; Laetitia Bonifait; Marylise Perivier; Marcelo Gottschalk; Daniel Grenier
Journal:  BMC Microbiol       Date:  2015-04-04       Impact factor: 3.605

8.  Quantitative proteomic analysis of gastric cancer tissue reveals novel proteins in platelet-derived growth factor b signaling pathway.

Authors:  Fang Liu; Yuan Zhang; Tingting Men; Xingyue Jiang; Chunhua Yang; He Li; Xiaodan Wei; Dong Yan; Gangming Feng; Jianke Yang; Jonas Bergquist; Bin Wang; Wenguo Jiang; Jia Mi; Geng Tian
Journal:  Oncotarget       Date:  2017-03-28
  8 in total

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