| Literature DB >> 19328691 |
Kerstin Rohr1, Rainer Mahrwald.
Abstract
An efficient tandem aldol condensation/Michael addition process of unactivated aldehydes and 1,3-cyclohexanedione is described. This transformation proceeds without any catalyst at room temperature with high isolated yields. By a fine-tuning of reaction conditions an access to both the aldol condensation/Michael addition products or to the dehydrated cyclized 9-substituted 1,8-dioxo-xanthenes is given.Entities:
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Year: 2009 PMID： 19328691 DOI： 10.1016/j.bmcl.2009.03.040
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823