Literature DB >> 19328062

It takes two binding sites for calcineurin and NFAT to tango.

Jun O Liu1, Benjamin A Nacev, Jing Xu, Shridhar Bhat.   

Abstract

In a recent issue of Molecular Cell, Rodríguez et al. (2009) identified the NFAT LxVP motif binding site as the same composite surface formed by the two calcineurin subunits that is recognized by the cyclophilin-CsA and FKBP-FK506 complexes.

Entities:  

Mesh:

Substances:

Year:  2009        PMID: 19328062     DOI: 10.1016/j.molcel.2009.03.005

Source DB:  PubMed          Journal:  Mol Cell        ISSN: 1097-2765            Impact factor:   17.970


  5 in total

Review 1.  Calcineurin signaling in the heart: The importance of time and place.

Authors:  Valentina Parra; Beverly A Rothermel
Journal:  J Mol Cell Cardiol       Date:  2016-12-20       Impact factor: 5.000

Review 2.  Calcineurin in the heart: New horizons for an old friend.

Authors:  Malay Chaklader; Beverly A Rothermel
Journal:  Cell Signal       Date:  2021-08-25       Impact factor: 4.315

3.  FHL2 binds calcineurin and represses pathological cardiac growth.

Authors:  Berdymammet Hojayev; Beverly A Rothermel; Thomas G Gillette; Joseph A Hill
Journal:  Mol Cell Biol       Date:  2012-07-30       Impact factor: 4.272

4.  The optimized core peptide derived from CABIN1 efficiently inhibits calcineurin-mediated T-cell activation.

Authors:  Sangho Lee; Han-Teo Lee; Young Ah Kim; Il-Hwan Lee; Seong-Jun Kang; Kyeongpyo Sim; Chung-Gyu Park; Kyungho Choi; Hong-Duk Youn
Journal:  Exp Mol Med       Date:  2022-05-12       Impact factor: 12.153

Review 5.  Calcineurin.

Authors:  Trevor P Creamer
Journal:  Cell Commun Signal       Date:  2020-08-28       Impact factor: 5.712

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.