Literature DB >> 19328060

Changing of the guard: how ATM hands off DNA double-strand break signaling to ATR.

Nicholas Rhind1.   

Abstract

In a recent issue of Molecular Cell, Shiotani and Zou (2009) elucidate the biochemical mechanism underlying sequential ATM and ATR activation at DNA double-strand breaks, demonstrating that resection transforms ATM substrates into ATR substrates.

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Year:  2009        PMID： 19328060      PMCID： PMC2861554          DOI： 10.1016/j.molcel.2009.03.004

Source DB:  PubMed          Journal:  Mol Cell        ISSN： 1097-2765            Impact factor:   17.970


  11 in total

1.  ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex.

Authors:  Ji-Hoon Lee; Tanya T Paull
Journal:  Science       Date:  2005-03-24       Impact factor: 47.728

2.  Two-step activation of ATM by DNA and the Mre11-Rad50-Nbs1 complex.

Authors:  Aude Dupré; Louise Boyer-Chatenet; Jean Gautier
Journal:  Nat Struct Mol Biol       Date:  2006-04-23       Impact factor: 15.369

3.  The structural determinants of checkpoint activation.

Authors:  Christina A MacDougall; Tony S Byun; Christopher Van; Muh-ching Yee; Karlene A Cimprich
Journal:  Genes Dev       Date:  2007-04-15       Impact factor: 11.361

4.  ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks.

Authors:  Ali Jazayeri; Jacob Falck; Claudia Lukas; Jiri Bartek; Graeme C M Smith; Jiri Lukas; Stephen P Jackson
Journal:  Nat Cell Biol       Date:  2005-12-04       Impact factor: 28.824

5.  Rapid activation of ATR by ionizing radiation requires ATM and Mre11.

Authors:  Jeremy S Myers; David Cortez
Journal:  J Biol Chem       Date:  2006-01-23       Impact factor: 5.157

6.  Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends.

Authors:  Zhu Zhu; Woo-Hyun Chung; Eun Yong Shim; Sang Eun Lee; Grzegorz Ira
Journal:  Cell       Date:  2008-09-19       Impact factor: 41.582

7.  Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing.

Authors:  Eleni P Mimitou; Lorraine S Symington
Journal:  Nature       Date:  2008-09-21       Impact factor: 49.962

8.  Reconstitution of a human ATR-mediated checkpoint response to damaged DNA.

Authors:  Jun-Hyuk Choi; Laura A Lindsey-Boltz; Aziz Sancar
Journal:  Proc Natl Acad Sci U S A       Date:  2007-08-08       Impact factor: 11.205

9.  Ataxia-telangiectasia mutated (ATM)-dependent activation of ATR occurs through phosphorylation of TopBP1 by ATM.

Authors:  Hae Yong Yoo; Akiko Kumagai; Anna Shevchenko; Andrej Shevchenko; William G Dunphy
Journal:  J Biol Chem       Date:  2007-04-19       Impact factor: 5.157

10.  DNA helicases Sgs1 and BLM promote DNA double-strand break resection.

Authors:  Serge Gravel; J Ross Chapman; Christine Magill; Stephen P Jackson
Journal:  Genes Dev       Date:  2008-10-15       Impact factor: 11.361
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  6 in total

1.  MRE11 and COM1/SAE2 are required for double-strand break repair and efficient chromosome pairing during meiosis of the protist Tetrahymena.

Authors:  Agnieszka Lukaszewicz; Rachel A Howard-Till; Maria Novatchkova; Kazufumi Mochizuki; Josef Loidl
Journal:  Chromosoma       Date:  2010-04-27       Impact factor: 4.316

Review 2.  The Intra-S Checkpoint Responses to DNA Damage.

Authors:  Divya Ramalingam Iyer; Nicholas Rhind
Journal:  Genes (Basel)       Date:  2017-02-17       Impact factor: 4.096

Review 3.  Regulation of programmed death-ligand 1 expression in response to DNA damage in cancer cells: Implications for precision medicine.

Authors:  Hiro Sato; Penny A Jeggo; Atsushi Shibata
Journal:  Cancer Sci       Date:  2019-10-04       Impact factor: 6.716

4.  Nucleosome disassembly during human non-homologous end joining followed by concerted HIRA- and CAF-1-dependent reassembly.

Authors:  Xuan Li; Jessica K Tyler
Journal:  Elife       Date:  2016-06-08       Impact factor: 8.140

5.  Inhibition of the HDAC/Suv39/G9a pathway restores the expression of DNA damage-dependent major histocompatibility complex class I-related chain A and B in cancer cells.

Authors:  Nakako Izumi Nakajima; Atsuko Niimi; Mayu Isono; Takahiro Oike; Hiro Sato; Takashi Nakano; Atsushi Shibata
Journal:  Oncol Rep       Date:  2017-06-30       Impact factor: 3.906

6.  High linear energy transfer carbon-ion irradiation upregulates PD-L1 expression more significantly than X-rays in human osteosarcoma U2OS cells.

Authors:  Tiara Bunga Mayang Permata; Hiro Sato; Wenchao Gu; Sangeeta Kakoti; Yuki Uchihara; Yukihiko Yoshimatsu; Itaru Sato; Reona Kato; Motohiro Yamauchi; Keiji Suzuki; Takahiro Oike; Yoshito Tsushima; Soehartati Gondhowiardjo; Tatsuya Ohno; Takaaki Yasuhara; Atsushi Shibata
Journal:  J Radiat Res       Date:  2021-09-13       Impact factor: 2.724
  6 in total

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