OBJECTIVE: To describe a case of ovarian luteinized thecoma, a rare ovarian neoplasm, which is only the 26th reported case associated with sclerosing peritonitis. DESIGN: Case report. SETTING: NYU Fertility Center and Memorial Hospital for Cancer and Allied Diseases, New York. PATIENT(S): A 17-year-old woman presenting with a large pelvic mass and abdominal pain. INTERVENTION(S): Conservative surgical treatment with laparotomy, unilateral salpingooophorectomy, and biopsy of contralateral ovary. Gonadotropin-releasing hormone agonist suppression. Ovarian hyperstimulation with oocyte retrieval/freezing to preserve biologic fertility. MAIN OUTCOME MEASURE(S): Response to conservative therapy and oocyte cryopreservation as a method of fertility preservation. RESULT(S): At laparotomy, obvious unilateral ovarian involvement was present, and a left salpingoophorectomy was performed. Biopsy of the contralateral ovary confirmed bilateral disease. The initial pathological review was complicated by extensive ovarian edema. The patient was treated with gonadotropin-releasing hormone agonist suppression plus intermittent estradiol supplementation. When she became intolerant of hormone therapy and when removal of the remaining ovary became a possibility, she underwent ovarian hyperstimulation; oocyte retrieval and freezing were performed to preserve her biologic fertility. Thirty-eight eggs were obtained. CONCLUSION(S): Surgically diagnosed luteinized thecoma can be managed medically. Oocyte cryopreservation as a means of fertility preservation should be considered in young women with this diagnosis who are at risk for bilateral gonad removal.
OBJECTIVE: To describe a case of ovarian luteinized thecoma, a rare ovarian neoplasm, which is only the 26th reported case associated with sclerosing peritonitis. DESIGN: Case report. SETTING: NYU Fertility Center and Memorial Hospital for Cancer and Allied Diseases, New York. PATIENT(S): A 17-year-old woman presenting with a large pelvic mass and abdominal pain. INTERVENTION(S): Conservative surgical treatment with laparotomy, unilateral salpingooophorectomy, and biopsy of contralateral ovary. Gonadotropin-releasing hormone agonist suppression. Ovarian hyperstimulation with oocyte retrieval/freezing to preserve biologic fertility. MAIN OUTCOME MEASURE(S): Response to conservative therapy and oocyte cryopreservation as a method of fertility preservation. RESULT(S): At laparotomy, obvious unilateral ovarian involvement was present, and a left salpingoophorectomy was performed. Biopsy of the contralateral ovary confirmed bilateral disease. The initial pathological review was complicated by extensive ovarian edema. The patient was treated with gonadotropin-releasing hormone agonist suppression plus intermittent estradiol supplementation. When she became intolerant of hormone therapy and when removal of the remaining ovary became a possibility, she underwent ovarian hyperstimulation; oocyte retrieval and freezing were performed to preserve her biologic fertility. Thirty-eight eggs were obtained. CONCLUSION(S): Surgically diagnosed luteinized thecoma can be managed medically. Oocyte cryopreservation as a means of fertility preservation should be considered in young women with this diagnosis who are at risk for bilateral gonad removal.
Authors: Diane Chen; Lia A Bernardi; Mary Ellen Pavone; Eve C Feinberg; Molly B Moravek Journal: J Assist Reprod Genet Date: 2018-08-22 Impact factor: 3.412