| Literature DB >> 19327589 |
Grover C Bagby1, Gabrielle Meyers.
Abstract
Patients who have acquired and inherited bone marrow failure syndromes are at risk for the development of clonal neoplasms including acute myeloid leukemia, myelodysplastic syndrome, and paroxysmal nocturnal hemoglobinuria. This article reviews the evidence supporting a model of clonal selection, a paradigm that provides a reasonable expectation that these often fatal complications might be prevented in the future.Entities:
Mesh:
Substances:
Year: 2009 PMID: 19327589 PMCID: PMC2697169 DOI: 10.1016/j.hoc.2009.01.006
Source DB: PubMed Journal: Hematol Oncol Clin North Am ISSN: 0889-8588 Impact factor: 3.722