| Literature DB >> 19327241 |
C E Papagoras1, M I Argyropoulou, P V Voulgari, I Vrabie, A K Zikou, A A Drosos.
Abstract
A 69-year-old woman with psoriatic arthritis treated with infliximab presented with low back pain of recent onset and fever. Serological, microbiological and imaging studies revealed Brucella spondylitis at the L5-S1 level. Immunosuppressive therapy was suspended and antibiotic therapy including doxycycline and rifampicin was administered for six months. The patient responded adequately with clinical and laboratory improvement and a considerable remission of spondylitis on repeat magnetic resonance imaging scan. The pathophysiology of tumor necrosis factor (TNF) alpha in Brucellosis and the role of anti-TNFalpha therapy are discussed.Entities:
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Year: 2009 PMID： 19327241
Source DB: PubMed Journal: Clin Exp Rheumatol ISSN： 0392-856X Impact factor: 4.473