Literature DB >> 19324136

Fewer grafts performed in off-pump bypass surgery: patient selection or incomplete revascularization?

Mitchell J Magee1, Emily Hebert, Morley A Herbert, Syma L Prince, Todd M Dewey, Dan V Culica, Michael J Mack.   

Abstract

BACKGROUND: Comparisons of off-pump (OPCAB) versus conventional on-pump coronary artery bypass (CCAB) consistently report fewer grafts per patient with OPCAB. Performing fewer grafts than indicated based on angiographic assessment could result in incomplete revascularization. We questioned whether OPCAB influenced surgeons to perform fewer grafts than needed.
METHODS: Preoperative angiographic and surgical data were collected prospectively on 945 patients undergoing coronary artery bypass grafting (370 OPCAB, 575 CCAB) at 8 hospitals between February 1, 2004, and July 31, 2004. The number of grafts needed per patient was determined from the reported number of vessels with angiographic stenoses of 50% or greater, and compared with the number received per patient, stratified by coronary artery bypass grafting technique.
RESULTS: The OPCAB and CCAB groups were demographically similar. The mean number of grafts needed per patient was significantly less in the OPCAB group (2.95 versus 3.48), accounting for fewer grafts received in that group (2.75 versus 3.36). The ratio of grafts (received/needed) was the same in both groups. Patients receiving more than three grafts were more likely to have CCAB (71.2%), whereas those receiving fewer than three grafts were almost as likely to have OPCAB as CCAB (55.5%). The rate of 1-year major adverse events (death, myocardial infarction, repeat revascularization) was the same in OPCAB and CCAB (15.5% versus 14.1%; p = 0.57).
CONCLUSIONS: Completeness of revascularization, determined by comparing the number of grafts performed to the number needed, was equivalent in OPCAB and CCAB patients, and 18-month clinical outcomes were equivalent. Preferential selection of patients needing more bypass grafts to CCAB results in the lower mean number of grafts per patient with OPCAB.

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Year:  2009        PMID: 19324136     DOI: 10.1016/j.athoracsur.2008.12.088

Source DB:  PubMed          Journal:  Ann Thorac Surg        ISSN: 0003-4975            Impact factor:   4.330


  7 in total

Review 1.  Off-pump coronary artery bypass grafting: Misperceptions and misconceptions.

Authors:  Shahzad G Raja; Umberto Benedetto
Journal:  World J Methodol       Date:  2014-03-26

Review 2.  Impact of incomplete surgical revascularization on survival.

Authors:  Miguel Guerra; João Carlos Mota
Journal:  Interact Cardiovasc Thorac Surg       Date:  2011-11-28

Review 3.  Off-Pump Coronary Artery Bypass Grafting; is it Still Relevant?

Authors:  Chima K P Ofoegbu; Rodgers M Manganyi
Journal:  Curr Cardiol Rev       Date:  2022

4.  Off-pump or minimized on-pump coronary surgery--initial experience with Circulating Endothelial Cells (CEC) as a supersensitive marker of tissue damage.

Authors:  Thorsten Wittwer; Yeong-Hoon Choi; Klaus Neef; Mareike Schink; Anton Sabashnikov; Thorsten Wahlers
Journal:  J Cardiothorac Surg       Date:  2011-10-19       Impact factor: 1.637

Review 5.  On-pump versus off-pump coronary artery bypass graft surgery: what do the evidence show?

Authors:  Alfredo José Rodrigues; Paulo Roberto Barbosa Evora; Paulo Victor Alves Tubino
Journal:  Rev Bras Cir Cardiovasc       Date:  2013 Oct-Dec

Review 6.  Off-Pump Coronary Artery Bypass Grafting: 30 Years of Debate.

Authors:  Mario Gaudino; Gianni D Angelini; Charalambos Antoniades; Faisal Bakaeen; Umberto Benedetto; Antonio M Calafiore; Antonino Di Franco; Michele Di Mauro; Stephen E Fremes; Leonard N Girardi; David Glineur; Juan Grau; Guo-Wei He; Carlo Patrono; John D Puskas; Marc Ruel; Thomas A Schwann; Derrick Y Tam; James Tatoulis; Robert Tranbaugh; Michael Vallely; Marco A Zenati; Michael Mack; David P Taggart
Journal:  J Am Heart Assoc       Date:  2018-08-21       Impact factor: 5.501

7.  Analysis of Myocardial Ischemia Parameters after Coronary Artery Bypass Grafting with Minimal Extracorporeal Circulation and a Novel Microplegia versus Off-Pump Coronary Artery Bypass Grafting.

Authors:  Luca Koechlin; Urs Zenklusen; Thomas Doebele; Bejtush Rrahmani; Brigitta Gahl; Thibault Schaeffer; Denis Berdajs; Friedrich S Eckstein; Oliver Reuthebuch
Journal:  Mediators Inflamm       Date:  2020-01-25       Impact factor: 4.711

  7 in total

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