Literature DB >> 19321696

Good performance of immunoglobulin M assays in diagnosing genotype 3 hepatitis E virus infections.

Florence Legrand-Abravanel1, Isabelle Thevenet, Jean-Michel Mansuy, Karine Saune, Françoise Vischi, Jean-Marie Peron, Nassim Kamar, Lionel Rostaing, Jacques Izopet.   

Abstract

We have evaluated three anti-hepatitis E virus (anti-HEV) immunoglobulin M (IgM) assays, the EIAgen HEV IgM assay (Adaltis), the HEV IgM enzyme-linked immunosorbent assay 3.0, and the Assure HEV IgM rapid test (MP Diagnostics), for the routine detection of acute genotype 3 HEV. Their sensitivities were fairly good (90%, 88%, and 82%), and their specificities were excellent (100%, 99.5%, and 100%).

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Year:  2009        PMID： 19321696      PMCID： PMC2681577          DOI： 10.1128/CVI.00438-08

Source DB:  PubMed          Journal:  Clin Vaccine Immunol        ISSN： 1556-679X


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5.  Detection of sporadic cases of hepatitis E virus (HEV) infection in China using immunoassays based on recombinant open reading frame 2 and 3 polypeptides from HEV genotype 4.

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6.  Diagnostic value of immunoglobulin G (IgG) and IgM anti-hepatitis E virus (HEV) tests based on HEV RNA in an area where hepatitis E is not endemic.

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7.  Hepatitis E in patients with hepatic disorders and HIV-infected patients in Croatia: is one diagnostic method enough for hepatitis E diagnosis?

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8.  Performance of two commercial assays for detecting hepatitis E virus RNA in acute or chronic infections.

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