Literature DB >> 1932118

Hem-1, a potential membrane protein, with expression restricted to blood cells.

R Hromas1, S Collins, W Raskind, L Deaven, K Kaushansky.   

Abstract

Overlapping cDNAs 3.8 kb in length containing a long open reading frame were obtained that hybridized exclusively to transcripts from hematopoietic cells. Sequence analysis found eight potential membrane domains and two possible cAMP/cGMP phosphorylation sites. This sequence exhibited no homologies with the EMBL/Genbank nucleic acid, SwissProt or GenPept amino acid data bases. The gene is located at 12q13.1, a region of occasional translocations in hematopoietic neoplasia and a rare folic acid fragile site, Fra 12A.

Entities:  

Mesh：

Substances：

Year:  1991        PMID： 1932118     DOI： 10.1016/0167-4781(91)90109-y

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  11 in total

1.  The WAVE2 complex regulates actin cytoskeletal reorganization and CRAC-mediated calcium entry during T cell activation.

Authors:  Jeffrey C Nolz; Timothy S Gomez; Peimin Zhu; Shuixing Li; Ricardo B Medeiros; Yoji Shimizu; Janis K Burkhardt; Bruce D Freedman; Daniel D Billadeau
Journal:  Curr Biol       Date:  2006-01-10       Impact factor: 10.834

2.  Nap1-mediated actin remodeling is essential for mammalian myoblast fusion.

Authors:  Scott J Nowak; Patrick C Nahirney; Anna-Katerina Hadjantonakis; Mary K Baylies
Journal:  J Cell Sci       Date:  2009-08-25       Impact factor: 5.285

3.  Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes.

Authors:  Alexander Leithner; Alexander Eichner; Jan Müller; Anne Reversat; Markus Brown; Jan Schwarz; Jack Merrin; David J J de Gorter; Florian Schur; Jonathan Bayerl; Ingrid de Vries; Stefan Wieser; Robert Hauschild; Frank P L Lai; Markus Moser; Dontscho Kerjaschki; Klemens Rottner; J Victor Small; Theresia E B Stradal; Michael Sixt
Journal:  Nat Cell Biol       Date:  2016-10-24       Impact factor: 28.824

Review 4.  When Actin is Not Actin' Like It Should: A New Category of Distinct Primary Immunodeficiency Disorders.

Authors:  Evelien G G Sprenkeler; Steven D S Webbers; Taco W Kuijpers
Journal:  J Innate Immun       Date:  2020-08-26       Impact factor: 7.349

Review 5.  Hem-1: putting the "WAVE" into actin polymerization during an immune response.

Authors:  Heon Park; Maia M Chan; Brian M Iritani
Journal:  FEBS Lett       Date:  2010-10-20       Impact factor: 4.124

6.  Hem-1 complexes are essential for Rac activation, actin polymerization, and myosin regulation during neutrophil chemotaxis.

Authors:  Orion D Weiner; Maike C Rentel; Alex Ott; Glenn E Brown; Mark Jedrychowski; Michael B Yaffe; Steven P Gygi; Lewis C Cantley; Henry R Bourne; Marc W Kirschner
Journal:  PLoS Biol       Date:  2006-01-24       Impact factor: 8.029

7.  Homer3 regulates the establishment of neutrophil polarity.

Authors:  Julie Wu; Anne Pipathsouk; A Keizer-Gunnink; F Fusetti; W Alkema; Shanshan Liu; Steven Altschuler; Lani Wu; Arjan Kortholt; Orion D Weiner
Journal:  Mol Biol Cell       Date:  2015-03-04       Impact factor: 4.138

8.  The Wave2 scaffold Hem-1 is required for transition of fetal liver hematopoiesis to bone marrow.

Authors:  Lijian Shao; Jianhui Chang; Wei Feng; Xiaoyan Wang; Elizabeth A Williamson; Ying Li; Amir Schajnovitz; David Scadden; Luke J Mortensen; Charles P Lin; Linheng Li; Ariel Paulson; James Downing; Daohong Zhou; Robert A Hromas
Journal:  Nat Commun       Date:  2018-06-18       Impact factor: 14.919

9.  The actin-regulatory protein Hem-1 is essential for alveolar macrophage development.

Authors:  Nutthakarn Suwankitwat; Stephen Libby; H Denny Liggitt; Alan Avalos; Alanna Ruddell; Jason W Rosch; Heon Park; Brian M Iritani
Journal:  J Exp Med       Date:  2021-04-05       Impact factor: 14.307

10.  A point mutation in the murine Hem1 gene reveals an essential role for Hematopoietic protein 1 in lymphopoiesis and innate immunity.

Authors:  Heon Park; Karen Staehling-Hampton; Mark W Appleby; Mary E Brunkow; Tania Habib; Yi Zhang; Fred Ramsdell; H Denny Liggitt; Brian Freie; Mark Tsang; George Carlson; Sherree Friend; Charles Frevert; Brian M Iritani
Journal:  J Exp Med       Date:  2008-11-17       Impact factor: 14.307
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.