Literature DB >> 19321146

Innate immunity: cytoplasmic DNA sensing by the AIM2 inflammasome.

Kate Schroder1, Daniel A Muruve, Jürg Tschopp.   

Abstract

Cytoplasmic double-stranded DNA triggers cell death and secretion of the pro-inflammatory cytokine IL-1beta in macrophages. Recent reports now describe the mechanism underlying this observation. Upon sensing of DNA, the HIN-200 family member AIM2 triggers the assembly of the inflammasome, culminating in caspase-1 activation, IL-1beta maturation and pyroptotic cell death.

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Year:  2009        PMID： 19321146     DOI： 10.1016/j.cub.2009.02.011

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  64 in total

1.  Human cytomegalovirus pUL83 stimulates activity of the viral immediate-early promoter through its interaction with the cellular IFI16 protein.

Authors:  Ileana M Cristea; Nathaniel J Moorman; Scott S Terhune; Christian D Cuevas; Erin S O'Keefe; Michael P Rout; Brian T Chait; Thomas Shenk
Journal:  J Virol       Date:  2010-05-26       Impact factor: 5.103

2.  NLRP3-inflammasomes are triggered by age-related hearing loss in the inner ear of mice.

Authors:  Xi Shi; Shiwei Qiu; Wei Zhuang; Na Yuan; Caiji Wang; Shili Zhang; Tiantian Sun; Weiwei Guo; Fenglei Gao; Shiming Yang; Yuehua Qiao
Journal:  Am J Transl Res       Date:  2017-12-15       Impact factor: 4.060

3.  Cyclic-di-GMP and cyclic-di-AMP activate the NLRP3 inflammasome.

Authors:  Ali A Abdul-Sater; Ivan Tattoli; Lei Jin; Andrzej Grajkowski; Assaf Levi; Beverly H Koller; Irving C Allen; Serge L Beaucage; Katherine A Fitzgerald; Jenny P-Y Ting; John C Cambier; Stephen E Girardin; Christian Schindler
Journal:  EMBO Rep       Date:  2013-09-06       Impact factor: 8.807

4.  RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway.

Authors:  Yu-Hsin Chiu; John B Macmillan; Zhijian J Chen
Journal:  Cell       Date:  2009-07-23       Impact factor: 41.582

5.  New DNA-sensing pathway feeds RIG-I with RNA.

Authors:  Xuetao Cao
Journal:  Nat Immunol       Date:  2009-10       Impact factor: 25.606

6.  A selective contribution of the RIG-I-like receptor pathway to type I interferon responses activated by cytosolic DNA.

Authors:  Myoung Kwon Choi; ZhiChao Wang; Tatsuma Ban; Hideyuki Yanai; Yan Lu; Ryuji Koshiba; Yukana Nakaima; Sho Hangai; David Savitsky; Makoto Nakasato; Hideo Negishi; Osamu Takeuchi; Kenya Honda; Shizuo Akira; Tomohiko Tamura; Tadatsugu Taniguchi
Journal:  Proc Natl Acad Sci U S A       Date:  2009-10-01       Impact factor: 11.205

7.  Suppression of immune responses by nonimmunogenic oligodeoxynucleotides with high affinity for high-mobility group box proteins (HMGBs).

Authors:  Hideyuki Yanai; Shiho Chiba; Tatsuma Ban; Yukana Nakaima; Takashi Onoe; Kenya Honda; Hideki Ohdan; Tadatsugu Taniguchi
Journal:  Proc Natl Acad Sci U S A       Date:  2011-06-27       Impact factor: 11.205

8.  IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection.

Authors:  Nagaraj Kerur; Mohanan Valiya Veettil; Neelam Sharma-Walia; Virginie Bottero; Sathish Sadagopan; Pushpalatha Otageri; Bala Chandran
Journal:  Cell Host Microbe       Date:  2011-05-19       Impact factor: 21.023

Review 9.  The inflammasomes in health and disease: from genetics to molecular mechanisms of autoinflammation and beyond.

Authors:  Cristina Conforti-Andreoni; Paola Ricciardi-Castagnoli; Alessandra Mortellaro
Journal:  Cell Mol Immunol       Date:  2011-01-24       Impact factor: 11.530

10.  Endosomal Toll-Like Receptors Mediate Enhancement of Interleukin-17A Production Triggered by Epstein-Barr Virus DNA in Mice.

Authors:  Marwa Shehab; Nour Sherri; Hadi Hussein; Noor Salloum; Elias A Rahal
Journal:  J Virol       Date:  2019-09-30       Impact factor: 5.103
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