Literature DB >> 19319143

Antiviral immune responses: triggers of or triggered by autoimmunity?

Christian Münz1, Jan D Lünemann, Meghann Teague Getts, Stephen D Miller.   

Abstract

The predisposition of individuals to several common autoimmune diseases, such as rheumatoid arthritis, systemic lupus erythematosus and multiple sclerosis, is genetically linked to certain human MHC class II molecules and other immune modulators. However, genetic predisposition is only one risk factor for the development of these diseases, and low concordance rates in monozygotic twins, as well as the geographical distribution of disease risk, suggest the involvement of environmental factors in the development of these diseases. Among these environmental factors, infections have been implicated in the onset and/or promotion of autoimmunity. In this Review, we outline the mechanisms by which viral infection can trigger autoimmune disease and describe the pathways by which infection and immune control of infectious disease might be dysregulated during autoimmunity.

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Year:  2009        PMID： 19319143      PMCID： PMC2854652          DOI： 10.1038/nri2527

Source DB:  PubMed          Journal:  Nat Rev Immunol        ISSN： 1474-1733            Impact factor:   53.106


  140 in total

1.  Concordance for islet autoimmunity among monozygotic twins.

Authors:  Maria J Redondo; Joy Jeffrey; Pamela R Fain; George S Eisenbarth; Tihamer Orban
Journal:  N Engl J Med       Date:  2008-12-25       Impact factor: 91.245

2.  Broadened and elevated humoral immune response to EBNA1 in pediatric multiple sclerosis.

Authors:  J D Lünemann; P Huppke; S Roberts; W Brück; J Gärtner; C Münz
Journal:  Neurology       Date:  2008-09-23       Impact factor: 9.910

3.  Development of virus-specific CD4(+) T cells during primary cytomegalovirus infection.

Authors:  R J Rentenaar; L E Gamadia; N van DerHoek; F N van Diepen; R Boom; J F Weel; P M Wertheim-van Dillen; R A van Lier; I J ten Berge
Journal:  J Clin Invest       Date:  2000-02       Impact factor: 14.808

4.  Repertoire dynamics of autoreactive T cells in multiple sclerosis patients and healthy subjects: epitope spreading versus clonal persistence.

Authors:  N Goebels; H Hofstetter; S Schmidt; C Brunner; H Wekerle; R Hohlfeld
Journal:  Brain       Date:  2000-03       Impact factor: 13.501

5.  The intrathecal, polyspecific antiviral immune response: Specific for MS or a general marker of CNS autoimmunity?

Authors:  Sven Jarius; Peter Eichhorn; Christian Jacobi; Brigitte Wildemann; Manfred Wick; Raymond Voltz
Journal:  J Neurol Sci       Date:  2008-11-28       Impact factor: 3.181

6.  Human endogenous retrovirus-K18 Env as a risk factor in multiple sclerosis.

Authors:  A K Tai; E J O'Reilly; K A Alroy; K C Simon; K L Munger; B T Huber; A Ascherio
Journal:  Mult Scler       Date:  2008-08-13       Impact factor: 6.312

7.  Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.

Authors:  Sergio E Baranzini; Joanne Wang; Rachel A Gibson; Nicholas Galwey; Yvonne Naegelin; Frederik Barkhof; Ernst-Wilhelm Radue; Raija L P Lindberg; Bernard M G Uitdehaag; Michael R Johnson; Aspasia Angelakopoulou; Leslie Hall; Jill C Richardson; Rab K Prinjha; Achim Gass; Jeroen J G Geurts; Jolijn Kragt; Madeleine Sombekke; Hugo Vrenken; Pamela Qualley; Robin R Lincoln; Refujia Gomez; Stacy J Caillier; Michaela F George; Hourieh Mousavi; Rosa Guerrero; Darin T Okuda; Bruce A C Cree; Ari J Green; Emmanuelle Waubant; Douglas S Goodin; Daniel Pelletier; Paul M Matthews; Stephen L Hauser; Ludwig Kappos; Chris H Polman; Jorge R Oksenberg
Journal:  Hum Mol Genet       Date:  2008-11-14       Impact factor: 6.150

8.  Effects of infectious mononucleosis and HLA-DRB1*15 in multiple sclerosis.

Authors:  T R Nielsen; K Rostgaard; J Askling; R Steffensen; A Oturai; C Jersild; N Koch-Henriksen; P S Sørensen; H Hjalgrim
Journal:  Mult Scler       Date:  2009-01-19       Impact factor: 6.312

9.  Differential induction of experimental autoimmune encephalomyelitis by myelin basic protein molecular mimics in mice humanized for HLA-DR2 and an MBP(85-99)-specific T cell receptor.

Authors:  Maria T Greene; Anne M Ercolini; Mathew DeGutes; Stephen D Miller
Journal:  J Autoimmun       Date:  2008-11-12       Impact factor: 7.094

10.  CD4(+) T cell subsets during virus infection. Protective capacity depends on effector cytokine secretion and on migratory capability.

Authors:  K J Maloy; C Burkhart; T M Junt; B Odermatt; A Oxenius; L Piali; R M Zinkernagel; H Hengartner
Journal:  J Exp Med       Date:  2000-06-19       Impact factor: 14.307
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  183 in total

Review 1.  Immune modulation during latent herpesvirus infection.

Authors:  Douglas W White; R Suzanne Beard; Erik S Barton
Journal:  Immunol Rev       Date:  2012-01       Impact factor: 12.988

2.  Can maternal microchimeric cells influence the fetal response toward self antigens?

Authors:  Lucie Leveque; Kiarash Khosrotehrani
Journal:  Chimerism       Date:  2011-07-01

3.  Virus expanded regulatory T cells control disease severity in the Theiler's virus mouse model of MS.

Authors:  Maureen H Richards; Meghann Teague Getts; Joseph R Podojil; Young-Hee Jin; Byung S Kim; Stephen D Miller
Journal:  J Autoimmun       Date:  2011-01-26       Impact factor: 7.094

Review 4.  Polyreactive antibodies in adaptive immune responses to viruses.

Authors:  Hugo Mouquet; Michel C Nussenzweig
Journal:  Cell Mol Life Sci       Date:  2011-11-02       Impact factor: 9.261

5.  Up-regulation of fas and fasL pro-apoptotic genes expression in type 1 diabetes patients after autologous haematopoietic stem cell transplantation.

Authors:  G L V de Oliveira; K C R Malmegrim; A F Ferreira; R Tognon; S Kashima; C E B Couri; D T Covas; J C Voltarelli; F A de Castro
Journal:  Clin Exp Immunol       Date:  2012-06       Impact factor: 4.330

Review 6.  Immunology in the clinic review series; focus on type 1 diabetes and viruses: the innate immune response to enteroviruses and its possible role in regulating type 1 diabetes.

Authors:  K Lind; M H Hühn; M Flodström-Tullberg
Journal:  Clin Exp Immunol       Date:  2012-04       Impact factor: 4.330

7.  Chronic Toxoplasma gondii Infection Induces Anti-N-Methyl-d-Aspartate Receptor Autoantibodies and Associated Behavioral Changes and Neuropathology.

Authors:  Ye Li; Raphael P Viscidi; Geetha Kannan; Ross McFarland; Mikhail V Pletnikov; Emily G Severance; Robert H Yolken; Jianchun Xiao
Journal:  Infect Immun       Date:  2018-09-21       Impact factor: 3.441

Review 8.  Targeting the B7 family of co-stimulatory molecules: successes and challenges.

Authors:  Joseph R Podojil; Stephen D Miller
Journal:  BioDrugs       Date:  2013-02       Impact factor: 5.807

9.  Identification of a role for TRIM29 in the control of innate immunity in the respiratory tract.

Authors:  Junji Xing; Leiyun Weng; Bin Yuan; Zhuo Wang; Li Jia; Rui Jin; Hongbo Lu; Xian Chang Li; Yong-Jun Liu; Zhiqiang Zhang
Journal:  Nat Immunol       Date:  2016-10-03       Impact factor: 25.606

10.  Molecular mimicry between Anoctamin 2 and Epstein-Barr virus nuclear antigen 1 associates with multiple sclerosis risk.

Authors:  Katarina Tengvall; Jesse Huang; Cecilia Hellström; Patrick Kammer; Martin Biström; Burcu Ayoglu; Izaura Lima Bomfim; Pernilla Stridh; Julia Butt; Nicole Brenner; Angelika Michel; Karin Lundberg; Leonid Padyukov; Ingrid E Lundberg; Elisabet Svenungsson; Ingemar Ernberg; Sigurgeir Olafsson; Alexander T Dilthey; Jan Hillert; Lars Alfredsson; Peter Sundström; Peter Nilsson; Tim Waterboer; Tomas Olsson; Ingrid Kockum
Journal:  Proc Natl Acad Sci U S A       Date:  2019-08-02       Impact factor: 11.205
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