OBJECTIVES: Evaluate the first automated assay measuring a mid regional fragment of the proadrenomedullin (MR-proADM). DESIGN AND METHODS: B.R.A.H.M.S MR-proADM KRYPTOR is a homogeneous assay. RESULTS: In 144 healthy individuals, MR-proADM mean (SD) was measured at 0.37 nmol/L (0.09). High correlation with the manual assay, B.R.A.H.M.S MR-proADM LIA, was found on 281 samples from patients suffering from community acquired pneumonia (correlation coefficient 0.97). CONCLUSIONS: This fast assay can be used in low respiratory tract infections.
OBJECTIVES: Evaluate the first automated assay measuring a mid regional fragment of the proadrenomedullin (MR-proADM). DESIGN AND METHODS: B.R.A.H.M.S MR-proADM KRYPTOR is a homogeneous assay. RESULTS: In 144 healthy individuals, MR-proADM mean (SD) was measured at 0.37 nmol/L (0.09). High correlation with the manual assay, B.R.A.H.M.S MR-proADM LIA, was found on 281 samples from patients suffering from community acquired pneumonia (correlation coefficient 0.97). CONCLUSIONS: This fast assay can be used in low respiratory tract infections.
Authors: Alexander Kutz; Eva Grolimund; Mirjam Christ-Crain; Robert Thomann; Claudine Falconnier; Claus Hoess; Christoph Henzen; Werner Zimmerli; Beat Mueller; Philipp Schuetz Journal: BMC Anesthesiol Date: 2014-11-15 Impact factor: 2.217
Authors: Patrick Badertscher; Thomas Nestelberger; Jeanne du Fay de Lavallaz; Martin Than; Beata Morawiec; Damian Kawecki; Òscar Miró; Beatriz López; F Javier Martin-Sanchez; José Bustamante; Nicolas Geigy; Michael Christ; Salvatore Di Somma; W Frank Peacock; Louise Cullen; François Sarasin; Dayana Flores; Michael Tschuck; Jasper Boeddinghaus; Raphael Twerenbold; Karin Wildi; Zaid Sabti; Christian Puelacher; Maria Rubini Giménez; Nikola Kozhuharov; Samyut Shrestha; Ivo Strebel; Katharina Rentsch; Dagmar I Keller; Imke Poepping; Andreas Buser; Wanda Kloos; Jens Lohrmann; Michael Kuehne; Stefan Osswald; Tobias Reichlin; Christian Mueller Journal: J Am Heart Assoc Date: 2017-12-14 Impact factor: 5.501