Literature DB >> 1931473

Polymorphisms in oxidative drug metabolism: relationship to food preference.

M R Britto1, H E McKean, G G Bruckner, P J Wedlund.   

Abstract

To determine whether a correlation exists between polymorphisms of oxidative drug metabolism and dietary preference, 29 poor metabolizers of dextromethorphan, 18 poor metabolizers of mephenytoin and 134 extensive metabolizers of both drugs were screened for their preferences for various food items. Poor metabolizers of dextromethorphan showed a diminished stated preference for cauliflower and coconut, and poor metabolizers of mephenytoin showed a diminished stated preference for spinach and cabbage.

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Year:  1991        PMID： 1931473      PMCID： PMC1368449          DOI： 10.1111/j.1365-2125.1991.tb03887.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


  12 in total

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