Literature DB >> 1931226

Plant cardiac glycosides and digoxin Fab antibody.

K Cheung1, R Urech, L Taylor, P Duffy, D Radford.   

Abstract

The potential application of the Digoxin Fab antibody (Wellcome Digibind) in the clinical management of plant poisoning was investigated. The cardiac glycoside contents of various Australian plants were studied using immunoassay techniques. The cross-reactions of the Fab antibody and two digoxin assay antibodies against extracts of these plants were also studied. Results obtained indicated that the Digibind antibody cross-reacted with a wide range of glycosides contained in Australian plants and therefore could be of use in the treatment of life-threatening plant poisoning.

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Year:  1991        PMID: 1931226     DOI: 10.1111/j.1440-1754.1991.tb02546.x

Source DB:  PubMed          Journal:  J Paediatr Child Health        ISSN: 1034-4810            Impact factor:   1.954


  2 in total

Review 1.  Successful treatment of oleander intoxication (cardiac glycosides) with digoxin-specific Fab antibody fragments in a 7-year-old child: case report and review of literature.

Authors:  C Camphausen; N A Haas; A C Mattke
Journal:  Z Kardiol       Date:  2005-12

2.  Controversial COVID-19 Cures: Hydroxychloroquine and Oleander Pediatric Ingestion Simulation Cases.

Authors:  Joshua J Solano; Rebecca A Mendelsohn; Rami A Ahmed; Richard D Shih; Lisa M Clayton; Scott M Alter; Patrick G Hughes
Journal:  Cureus       Date:  2022-06-21
  2 in total

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