Literature DB >> 1931131

Conjugation of capsular polysaccharide to alpha-haemolysin from Staphylococcus aureus as a glycoprotein antigen.

L Reynaud-Rondier1, A Voiland, G Michel.   

Abstract

The capsular polysaccharides of two pathogenic strains of Staphylococcus aureus 8914 and 31 were isolated and purified. These polysaccharides were conjugated to alpha-haemolysin prepared from the same strains. Amongst the various coupling procedures which were tested the best results were obtained with sodium cyanoborohydride and glutaraldehyde. The conjugates were purified and their immunologic properties were tested. They gave a positive response against antisera from whole bacterial cells.

Entities:  

Mesh:

Substances:

Year:  1991        PMID: 1931131     DOI: 10.1111/j.1574-6968.1991.tb04214.x

Source DB:  PubMed          Journal:  FEMS Microbiol Immunol        ISSN: 0920-8534


  3 in total

1.  Protein antigens increase the protective efficacy of a capsule-based vaccine against Staphylococcus aureus in a rat model of osteomyelitis.

Authors:  Santiago M Lattar; Mariángeles Noto Llana; Philippe Denoël; Sophie Germain; Fernanda R Buzzola; Jean C Lee; Daniel O Sordelli
Journal:  Infect Immun       Date:  2013-10-14       Impact factor: 3.441

Review 2.  Staphylococcus aureus capsular polysaccharides.

Authors:  Katherine O'Riordan; Jean C Lee
Journal:  Clin Microbiol Rev       Date:  2004-01       Impact factor: 26.132

3.  Antibodies to capsular polysaccharides are not protective against experimental Staphylococcus aureus endocarditis.

Authors:  J Nemeth; J C Lee
Journal:  Infect Immun       Date:  1995-02       Impact factor: 3.441

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.