Literature DB >> 19308593

A tale of two tibias: a review of treatment options for congenital pseudarthrosis of the tibia.

Charles E Johnston1, John G Birch.   

Abstract

PURPOSE: Two common treatment options for congenital pseudarthrosis of the tibia (CPT) are intramedullary fixation following resection/shortening of the pseudarthrosis site and reconstruction with an Ilizarov external fixator following resection. We present in detail a narrative of two cases with similar degrees of tibial dysplasia associated with NF-1 treated using these different methods and followed to completion.
METHODS: Technical issues and details of the treatment methods from case reports are discussed in depth. The eventual profoundly different outcomes are correlated to the technical variations used.
RESULTS: Treatment with the Charnley-Williams rodding method and aggressive bone grafting supplemented by rh-BMP2 resulted in a normal functioning limb at maturity, while treatment with first, an ineffective version of IM rodding, followed by two sessions of bone transport using an Ilizarov fixator failed to gain useful union and eventually resulted in amputation.
CONCLUSIONS: Technical details, heretofore inadequately reviewed in the literature, are crucial to the success of either of these commonly utilized treatment methods for CPT.

Entities:  

Year:  2008        PMID: 19308593      PMCID: PMC2656794          DOI: 10.1007/s11832-008-0084-2

Source DB:  PubMed          Journal:  J Child Orthop        ISSN: 1863-2521            Impact factor:   1.548


  16 in total

1.  The fibula in congenital pseudoarthrosis of the tibia: the EPOS multicenter study. European Paediatric Orthopaedic Society (EPOS).

Authors:  D Keret; G Bollini; P Dungl; J Fixsen; F Grill; F Hefti; E Ippolito; B Romanus; C Tudisco; S Wientroub
Journal:  J Pediatr Orthop B       Date:  2000-04       Impact factor: 1.041

2.  FRAGMENTATION AND RODDING IN OSTEOGENESIS IMPERFECTA.

Authors:  P F WILLIAMS
Journal:  J Bone Joint Surg Br       Date:  1965-02

3.  Congenital pseudarthrosis of the tibia treated by intramedullary nail.

Authors:  J CHARNLEY
Journal:  J Bone Joint Surg Am       Date:  1956-04       Impact factor: 5.284

4.  Gait analysis and muscle strength in children with congenital pseudarthrosis of the tibia: the effect of treatment.

Authors:  L A Karol; N F Haideri; S E Halliday; T B Smitherman; C E Johnston
Journal:  J Pediatr Orthop       Date:  1998 May-Jun       Impact factor: 2.324

5.  Congenital pseudarthrosis of the tibia associated with neurofibromatosis-1: treatment with Ilizarov's device.

Authors:  S Boero; M Catagni; O Donzelli; R Facchini; P V Frediani
Journal:  J Pediatr Orthop       Date:  1997 Sep-Oct       Impact factor: 2.324

6.  Ilizarov technique in the treatment of congenital pseudarthrosis of the tibia.

Authors:  I Ghanem; J P Damsin; H Carlioz
Journal:  J Pediatr Orthop       Date:  1997 Sep-Oct       Impact factor: 2.324

7.  Ultrastructure of congenital pseudarthrosis of the tibia.

Authors:  J Briner; E Yunis
Journal:  Arch Pathol       Date:  1973-02

8.  Treatment of congenital pseudoarthrosis of the tibia using the Ilizarov technique.

Authors:  D Paley; M Catagni; F Argnani; J Prevot; D Bell; P Armstrong
Journal:  Clin Orthop Relat Res       Date:  1992-07       Impact factor: 4.176

9.  The treatment of infected nonunions and segmental defects of the tibia by the methods of Ilizarov.

Authors:  R Cattaneo; M Catagni; E E Johnson
Journal:  Clin Orthop Relat Res       Date:  1992-07       Impact factor: 4.176

10.  Management of segmental defects by the Ilizarov intercalary bone transport method.

Authors:  S A Green; J M Jackson; D M Wall; H Marinow; J Ishkanian
Journal:  Clin Orthop Relat Res       Date:  1992-07       Impact factor: 4.176

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  9 in total

1.  Periosteal grafting for congenital pseudarthrosis of the tibia: a preliminary report.

Authors:  Ahmed M Thabet; Dror Paley; Mehmet Kocaoglu; Levent Eralp; John E Herzenberg; Omer Naci Ergin
Journal:  Clin Orthop Relat Res       Date:  2008-10-25       Impact factor: 4.176

Review 2.  Ilizarov treatment of congenital pseudarthrosis of the tibia: a multi-targeted approach using the Ilizarov technique.

Authors:  In Ho Choi; Tae-Joon Cho; Hyuk Ju Moon
Journal:  Clin Orthop Surg       Date:  2011-02-15

Review 3.  Diagnosis and treatment of osteopenic fractures in children.

Authors:  Charles T Mehlman; Marcia A Shepherd; Carie S Norris; Jessica B McCourt
Journal:  Curr Osteoporos Rep       Date:  2012-12       Impact factor: 5.096

4.  Management of congenital pseudarthrosis of the tibia with the Ilizarov method in a paediatric population: influence of aetiological factors.

Authors:  Dmitry Y Borzunov; Alexander Y Chevardin; Alexander I Mitrofanov
Journal:  Int Orthop       Date:  2015-11-07       Impact factor: 3.075

5.  Burnei's procedure in the treatment of long bone pseudarthrosis in patients having osteogenesis imperfecta or congenital pseudarthrosis of tibia - preliminary report.

Authors:  C Vlad; I Georgescu; T S Gavriliu; D I Hodorogea; T El Nayef; D Dan
Journal:  J Med Life       Date:  2012-06-18

6.  Congenital pseudarthrosis of the tibia: biological and biomechanical considerations to achieve union and prevent refracture.

Authors:  D Paley
Journal:  J Child Orthop       Date:  2019-04-01       Impact factor: 1.548

7.  New insights into osteogenic and chondrogenic differentiation of human bone marrow mesenchymal stem cells and their potential clinical applications for bone regeneration in pediatric orthopaedics.

Authors:  Nicola Giuliani; Gina Lisignoli; Marina Magnani; Costantina Racano; Marina Bolzoni; Benedetta Dalla Palma; Angelica Spolzino; Cristina Manferdini; Caterina Abati; Denise Toscani; Andrea Facchini; Franco Aversa
Journal:  Stem Cells Int       Date:  2013-05-23       Impact factor: 5.443

8.  Congenital pseudarthrosis of the tibia treated with a combination of Ilizarov's technique and intramedullary rodding.

Authors:  Mandar Vikas Agashe; Sang-Heon Song; Mohammad Ahmed Refai; Kwang-Won Park; Hae-Ryong Song
Journal:  Acta Orthop       Date:  2012-10-08       Impact factor: 3.717

9.  Short Term Results of a New Comprehensive Protocol for the Management of Congenital Pseudarthrosis of the Tibia.

Authors:  Sandeep Vijaykumar Vaidya; Alaric Aroojis; Rujuta Mehta; Mandar Vikas Agashe; Arjun Dhawale; Ankita Vijay Bansal; Kailash Sarathy
Journal:  Indian J Orthop       Date:  2019 Nov-Dec       Impact factor: 1.251

  9 in total

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