PURPOSE: This study has evaluated the effects of immobilization versus intermittent active motion on cartilage and on antibiotic efficacy in a rabbit septic arthritis model. METHODS: Rabbits were infected and assigned to one of four groups: group 1, no treatment without immobilization (allowing intermittent active motion); group 2, cast; group 3, oxacillin without immobilization; group 4, oxacillin and cast. Animals were sacrificed 21 days later. Bacterial counts and lateral radiograms were performed. A radiological score was calculated. RESULTS: Immobilization had no effect on oxacillin efficacy and a deleterious effect on the radiological score. CONCLUSION: Intermittent active motion has allowed a better cartilage healing during the treatment of septic arthritis.
PURPOSE: This study has evaluated the effects of immobilization versus intermittent active motion on cartilage and on antibiotic efficacy in a rabbit septic arthritis model. METHODS:Rabbits were infected and assigned to one of four groups: group 1, no treatment without immobilization (allowing intermittent active motion); group 2, cast; group 3, oxacillin without immobilization; group 4, oxacillin and cast. Animals were sacrificed 21 days later. Bacterial counts and lateral radiograms were performed. A radiological score was calculated. RESULTS: Immobilization had no effect on oxacillin efficacy and a deleterious effect on the radiological score. CONCLUSION: Intermittent active motion has allowed a better cartilage healing during the treatment of septic arthritis.
Authors: R B Salter; D F Simmonds; B W Malcolm; E J Rumble; D MacMichael; N D Clements Journal: J Bone Joint Surg Am Date: 1980-12 Impact factor: 5.284