Literature DB >> 19308502

Predicting the outcome of Legg-Calve-Perthes' disease in children under 6 years old.

Edward Gent1, Prasad Antapur, Rajnikant L Mehta, Vastara M Sudheer, Nicholas M P Clarke.   

Abstract

PURPOSE: In this study, we investigated the outcome of Legg-Calve-Perthes disease in children presenting under 6 years old. Firstly, we wished to know the outcome in terms of femoral head deformity in this age group. Secondly, we investigated the potential for improvement in femoral head deformity with growth and remodelling after the Perthes lesion had healed. Thirdly, we assessed the ability of Herring's lateral pillar classification to predict femoral head deformity in this age group.
METHODS: The outcome in this group was assessed using Stulberg's classification of femoral head deformity and compared to that for older children with Perthes seen at our institution over the same period. To investigate the potential for improvement of Stulberg grade with growth we assessed the hips at the stage of final healing (Waldenstrom IV) and again at skeletal maturity. To assess whether Herring's classification of lateral column collapse is predictive of deformity at this age we recorded the Herring class A, B or C at the time of maximum fragmentation and compared this to Stulberg grade.
RESULTS: Out of a total of 127 children (131 hips) seen at our institution, 67 children (69 hips) presented before the age of 6 years. The number of Stulberg III and IV hips was 14 (20%) and 10 (15%), respectively. Chi-squared test of age against outcome confirmed that the younger children overall had a better outcome (P < 0.001). Stulberg grade did not improve predictably after the stage of final healing. Twenty-three hips graded as Stulberg III and IV at Waldenstrom IV were reassessed at skeletal maturity. Three changed from Stulberg III to IV and five changed from Stulberg IV to III, but none had improved to Stulberg I/II. Herring's classification was predictive of outcome, with 96% of Herring A hips having Stulberg I or II outcome, 61% of Herring B hips having Stulberg I or II outcome, while 60% of Herring C hips (18 hips) had significant femoral head deformity, and 10 hips Stulberg III and 6 hips Stulberg IV.
CONCLUSIONS: Perthes in children presenting before 6 years of age can result in significant femoral head deformity which does not predictably improve with time. The risk of a poor outcome can be predicted by Herring's classification of lateral pillar collapse.

Entities:  

Year:  2007        PMID: 19308502      PMCID: PMC2656695          DOI: 10.1007/s11832-007-0007-7

Source DB:  PubMed          Journal:  J Child Orthop        ISSN: 1863-2521            Impact factor:   1.548


  12 in total

1.  Legg-Perthes disease in the young hip--does it necessarily do well?

Authors:  C R Snyder
Journal:  J Bone Joint Surg Am       Date:  1975-09       Impact factor: 5.284

2.  Optimal timing for containment surgery for Perthes disease.

Authors:  Benjamin Joseph; N Sreekumaran Nair; K L Narasimha Rao; Kishore Mulpuri; George Varghese
Journal:  J Pediatr Orthop       Date:  2003 Sep-Oct       Impact factor: 2.324

3.  Legg-Calve-Perthes disease. Part I: Classification of radiographs with use of the modified lateral pillar and Stulberg classifications.

Authors:  John A Herring; Hui Taek Kim; Richard Browne
Journal:  J Bone Joint Surg Am       Date:  2004-10       Impact factor: 5.284

4.  Evolution of femoral head deformity during the healing phase of Legg-Calvé-Perthes disease.

Authors:  J A Herring; J J Williams; J N Neustadt; J S Early
Journal:  J Pediatr Orthop       Date:  1993 Jan-Feb       Impact factor: 2.324

5.  Legg-Calvé-Perthes disease. Long-term evaluation of non-containment treatment.

Authors:  F B Kelly; S T Canale; R R Jones
Journal:  J Bone Joint Surg Am       Date:  1980-04       Impact factor: 5.284

6.  The natural history of Legg-Calvé-Perthes disease.

Authors:  S D Stulberg; D R Cooperman; R Wallensten
Journal:  J Bone Joint Surg Am       Date:  1981-09       Impact factor: 5.284

7.  Legg-Calvé-Perthes follow-up study.

Authors:  L Dekelver; G Fabry
Journal:  Arch Orthop Trauma Surg       Date:  1982

8.  Is there functional vascular information in anatomical MR sequences? A preliminary in vivo study.

Authors:  Renaud Winzenrieth; Isabelle Claude; Marie-Christine Hobatho; Guy Sebag
Journal:  IEEE Trans Biomed Eng       Date:  2006-06       Impact factor: 4.538

9.  RANKL inhibition: a novel strategy to decrease femoral head deformity after ischemic osteonecrosis.

Authors:  Harry K W Kim; Stephanie Morgan-Bagley; Paul Kostenuik
Journal:  J Bone Miner Res       Date:  2006-12       Impact factor: 6.741

10.  Femoral head vascularisation in Legg-Calvé-Perthes disease: comparison of dynamic gadolinium-enhanced subtraction MRI with bone scintigraphy.

Authors:  Sylvie Lamer; Sophie Dorgeret; Abdeslam Khairouni; Keyvan Mazda; Pierre-Yves Brillet; Eric Bacheville; Juliette Bloch; Georges F Penneçot; Max Hassan; Guy H Sebag
Journal:  Pediatr Radiol       Date:  2002-06-14
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  3 in total

1.  Treatment outcome in the most severely affected Legg-Perthes patients, comparing prolonged traction in abduction with femoral varus derotation treatment.

Authors:  F B M Wagenaar; C G B Maathuis; R H G P van Erve
Journal:  J Child Orthop       Date:  2010-12-14       Impact factor: 1.548

2.  Prognostic value of modified lateral pillar classification in Legg-Calvé-Perthes disease.

Authors:  Dam Seon Lee; Sung Taek Jung; Ki Hyeong Kim; Jae Joon Lee
Journal:  Clin Orthop Surg       Date:  2009-11-25

3.  Does early and aggressive management of significant extrusion of the femoral head affect the outcome of Perthes' disease with the age of onset younger than 7 years?

Authors:  K A Singh; N Harne; H Shah
Journal:  Musculoskelet Surg       Date:  2021-04-18
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