Literature DB >> 1930823

Structure of nortriptyline hydrochloride.

C L Klein1, T A Banks, D Rouselle.   

Abstract

C19H22N+.Cl-, Mr = 299.84, monoclinic, P2(1)/c, a = 5.070 (2), b = 34.088 (5), c = 9.976 (1) A, beta = 90.74 (2) degrees, V = 1724.0 A3, Z = 4, Dx = 1.16 g cm-3, lambda (Mo K alpha 1) = 0.70930 A, mu = 2.2 cm-1, F(000) = 640, T = 295 K, final R = 0.046 for 1381 observed reflections. The nortriptyline molecule crystallized with a 'butterfly' fold angle of 124.3 (2) degrees and an extended propylamino side chain. The amino nitrogen is involved in hydrogen bonds to two different chloride ions.

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Year:  1991        PMID: 1930823     DOI: 10.1107/s010827019001280x

Source DB:  PubMed          Journal:  Acta Crystallogr C        ISSN: 0108-2701            Impact factor:   1.172


  2 in total

1.  Nortriptyline reverses corticosteroid insensitivity by inhibition of phosphoinositide-3-kinase-δ.

Authors:  Nicolas Mercado; Yasuo To; Kazuhiro Ito; Peter J Barnes
Journal:  J Pharmacol Exp Ther       Date:  2011-02-07       Impact factor: 4.030

2.  Desipramine hydro-chloride: a non-merohedrally twinned structure.

Authors:  Jerry P Jasinski; Ray J Butcher; Q N M Hakim Al-Arique; H S Yathirajan; A R Ramesha
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-02-20
  2 in total

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