OBJECTIVE: To study the localization and size of residual anastomoses in twin-to-twin transfusion syndrome treated with fetoscopic laser surgery and correlate the findings with outcome. STUDY DESIGN: Placental injection in twin-to-twin transfusion syndrome placentas treated with laser was performed by using colored dye. RESULTS: A total of 77 twin-to-twin transfusion syndrome placentas were included in the study. Residual anastomoses (n = 48) were found in 32% (25/77) of lasered placentas. Most residual anastomoses were localized near the margin of the placenta. The majority of residual anastomoses (67%; 32/48) were very small (diameter, < 1 mm). Eleven of the 25 cases (44%) in the residual anastomoses group developed twin anemia-polycythemia sequence. CONCLUSION: Most residual anastomoses in twin-to-twin transfusion syndrome placentas treated with laser are very small and localized near the placental margin. Almost half of cases with residual anastomoses developed twin anemia-polycythemia sequence after laser surgery.
OBJECTIVE: To study the localization and size of residual anastomoses in twin-to-twin transfusion syndrome treated with fetoscopic laser surgery and correlate the findings with outcome. STUDY DESIGN: Placental injection in twin-to-twin transfusion syndrome placentas treated with laser was performed by using colored dye. RESULTS: A total of 77 twin-to-twin transfusion syndrome placentas were included in the study. Residual anastomoses (n = 48) were found in 32% (25/77) of lasered placentas. Most residual anastomoses were localized near the margin of the placenta. The majority of residual anastomoses (67%; 32/48) were very small (diameter, < 1 mm). Eleven of the 25 cases (44%) in the residual anastomoses group developed twin anemia-polycythemia sequence. CONCLUSION: Most residual anastomoses in twin-to-twin transfusion syndrome placentas treated with laser are very small and localized near the placental margin. Almost half of cases with residual anastomoses developed twin anemia-polycythemia sequence after laser surgery.
Authors: Enrico Lopriore; Femke Slaghekke; Johanna M Middeldorp; Frans J Klumper; Jan M van Lith; Frans J Walther; Dick Oepkes Journal: J Vis Exp Date: 2011-09-05 Impact factor: 1.355
Authors: Manon Gijtenbeek; Sanne J Eschbach; Johanna M Middeldorp; Frans J C M Klumper; Femke Slaghekke; Dick Oepkes; Monique C Haak Journal: Prenat Diagn Date: 2019-07-17 Impact factor: 3.050