Literature DB >> 19306376

Mild traumatic brain injury.

John J Bruns1, Andy S Jagoda.   

Abstract

Mild traumatic brain injury accounts for 1% to 2% of emergency department visits in the United States. Up to 15% of these patients will have an acute intracranial lesion identified on head computed tomography; less than 1% of mild traumatic brain injuries will require neurosurgical intervention. Clinical research over the past decade has focused on identifying the subgroup of patients with mild traumatic brain injury with acute traumatic lesions on computed tomography and specifically those at risk for harboring a potentially catastrophic lesion. This research has been used to generate evidence-based guidelines to assist in clinical decision making. There is no evidence to support the use of plain film radiographs in the evaluation of patients with mild traumatic brain injury. The utility of brain-specific biomarkers is rapidly evolving, and a growing body of evidence supports their potential role in determining the need for neuroimaging. Clinical predictors for identifying patients with abnormal computed tomography have been established and, if used, may have a significant positive impact on traumatic brain injury-related morbidity and healthcare utilization in the United States. Patients with negative computed tomography are at almost no risk of deteriorating; however, they should be counseled regarding postconcussive symptoms and should be given appropriate written instructions and referrals at discharge.

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Year:  2009        PMID: 19306376     DOI: 10.1002/msj.20101

Source DB:  PubMed          Journal:  Mt Sinai J Med        ISSN: 0027-2507


  16 in total

Review 1.  Current status of fluid biomarkers in mild traumatic brain injury.

Authors:  Jacqueline R Kulbe; James W Geddes
Journal:  Exp Neurol       Date:  2015-05-14       Impact factor: 5.330

Review 2.  Biomarkers in traumatic brain injury.

Authors:  Richa Sharma; Daniel T Laskowitz
Journal:  Curr Neurol Neurosci Rep       Date:  2012-10       Impact factor: 5.081

Review 3.  A review of magnetic resonance imaging and diffusion tensor imaging findings in mild traumatic brain injury.

Authors:  M E Shenton; H M Hamoda; J S Schneiderman; S Bouix; O Pasternak; Y Rathi; M-A Vu; M P Purohit; K Helmer; I Koerte; A P Lin; C-F Westin; R Kikinis; M Kubicki; R A Stern; R Zafonte
Journal:  Brain Imaging Behav       Date:  2012-06       Impact factor: 3.978

4.  Mild traumatic brain injury results in extensive neuronal degeneration in the cerebral cortex.

Authors:  Xiang Gao; Jinhui Chen
Journal:  J Neuropathol Exp Neurol       Date:  2011-03       Impact factor: 3.685

5.  Increase in blood-brain barrier permeability, oxidative stress, and activated microglia in a rat model of blast-induced traumatic brain injury.

Authors:  Ryan D Readnower; Mikulas Chavko; Saleena Adeeb; Michael D Conroy; James R Pauly; Richard M McCarron; Patrick G Sullivan
Journal:  J Neurosci Res       Date:  2010-09-29       Impact factor: 4.164

6.  Clinical significance of posttraumatic intracranial hemorrhage in clinically mild brain injury: a retrospective cohort study.

Authors:  Justin Z Wang; Christopher D Witiw; Nadia Scantlebury; Noah Ditkofsky; Avery B Nathens; Leodante da Costa
Journal:  CMAJ Open       Date:  2019-08-20

7.  MicroRNA let-7i is a promising serum biomarker for blast-induced traumatic brain injury.

Authors:  Nagaraja Balakathiresan; Manish Bhomia; Raghavendar Chandran; Mikulas Chavko; Richard M McCarron; Radha K Maheshwari
Journal:  J Neurotrauma       Date:  2012-04-13       Impact factor: 5.269

8.  Post-concussive syndrome after mild head trauma: epidemiological features in Tunisia.

Authors:  O Chakroun-Walha; I Rejeb; M Boujelben; K Chtara; A Mtibaa; H Ksibi; A Chaari; M Bouaziz; N Rekik
Journal:  Eur J Trauma Emerg Surg       Date:  2016-03-14       Impact factor: 3.693

9.  Improving the care of people with traumatic brain injury through the Neurotrauma Evidence Translation (NET) program: protocol for a program of research.

Authors:  Sally E Green; Marije Bosch; Joanne E McKenzie; Denise A O'Connor; Emma J Tavender; Peter Bragge; Marisa Chau; Veronica Pitt; Jeffrey V Rosenfeld; Russell L Gruen
Journal:  Implement Sci       Date:  2012-08-07       Impact factor: 7.327

10.  Application of blood-based biomarkers in human mild traumatic brain injury.

Authors:  Alex P Di Battista; Shawn G Rhind; Andrew J Baker
Journal:  Front Neurol       Date:  2013-05-01       Impact factor: 4.003

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