Literature DB >> 19305446

Live donor liver transplantation in New Zealand: a report on the first 20 cases.

John McCall1, Margaret Johnston, Barry Harrison, Ian Dittmer, Ron Benjamin, Yvonne Fullerton, Andrew Holden, Kerry Gunn, Peter Johnston, Ed Gane, David Orr, Simon Chin, Helen Evans, Stephen Mouat, Stephen Munn.   

Abstract

BACKGROUND: Liver transplantation (LT) is established treatment for adults and children with acute or chronic liver failure, however there are insufficient donor organs to meet demand and 14% of New Zealand patients have died waiting or were de-listed due to deterioration whilst on the waiting list. Live donor liver transplantation (LDLT) offers an alternative graft source that enables timely transplantation, but also carries the risk of morbidity and mortality for the donor. AIM: To report the initial experience with LDLT in New Zealand.
METHODS: Review of donor and recipient outcomes for the first 20 cases.
RESULTS: 129 potential live liver donors were assessed for 68 recipients. Donors were evaluated according to a multi-step protocol including independent donor advocacy. Twenty LDLT were performed on 7 adults and 13 paediatric recipients using 5 right lobe, 2 extended left lobe, 2 left lobe, and 11 left lateral section grafts. Five donors (25%) experienced postoperative complications, none of which were life-threatening. Four recipients had acute liver failure and 16 had chronic liver disease including one retransplant. There was a high rate of recipient biliary complications (40%) but graft and recipient survival is 100% to date.
CONCLUSION: LDLT has been successfully introduced in New Zealand with good donor and recipient outcomes.

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Year:  2009        PMID: 19305446

Source DB:  PubMed          Journal:  N Z Med J        ISSN: 0028-8446


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